ArticleCureus2026
Assessment of Biophysical Parameters and Acute Lesion Effectiveness in Atrial Fibrillation Ablation Using a Very High-Power Short-Duration Strategy.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRadiofrequency ablation (RFA) therapy is frequently performed to maintain sinus rhythm in patients with atrial fibrillation (AF).
objectiveThe purpose of this study was to assess the association between biophysical parameters (average contact force, maximum temperature, catheter stability, and impedance drop) and acute lesion effectiveness using a very high-power short-duration (90 W, 4 seconds, QDOT catheter, Biosense Webster, Irvine, California) ablation strategy for atrial fibrillation.
methodsWe analyzed 986 ablation lesions from 13 consecutive patients who underwent RFA between June and September 2024. After the pulmonary vein antral isolation (PVAI) lesion set, each lesion was assessed for the presence or absence of capture with high-output pacing (10 mA, 2 ms). Group A included lesions with no local capture, and Group B included lesions with local capture. Lesion characteristics were obtained from data stored in the CARTONET cloud-based platform (Biosense Webster). For each lesion, average contact force, maximum temperature, impedance drop, and catheter stability were analyzed. Statistical analysis was performed using independent t-tests, treating lesions as the unit of analysis.
resultsGroup A had more ablation lesions, higher contact force, a higher maximum temperature, and better stability compared with Group B (Group A vs Group B: 818 vs 168 lesions, p < 0.01; 19.47 g vs 17.58 g, p < 0.01; 44.96 °C vs 40.64 °C, p < 0.01; 1.59 mm vs 9.58 mm, p < 0.01). Group B had a higher impedance drop than Group A (10.35 Ω vs 8.27 Ω, p < 0.01). There were no major complications in either group at the 30-day follow-up.
conclusionHigher average contact force, higher temperature, and better stability were associated with successful lesion delivery utilizing a very high-power short-duration ablation strategy. In this cohort, an impedance drop beyond 8 Ω did not appear to be significantly associated with acute electrical isolation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.