Evidence map›Paper›PMID 42317923›Full record

ArticleCureus2026

Mixed Germ Cell Tumour in a 58-Year-Old Post-menopausal Woman: A Case Report.

Victor C Okebalama, Ogonna Arisi, Dorothy Oragwa, Bonaventure M Ogbodo, Olutomiwa Omokore, Kenelumchukwu Ekezie, Obioma Aririsukwu, Eberechuckwu Onyemachi, Nwora Oli, Onyebuchukwu Eke and 4 more

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Victor C OkebalamaHistopathology, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
Ogonna ArisiEmergency Medicine, University Hospital Coventry and Warwickshire NHS Trust, Coventry, GBR.
Dorothy OragwaEmergency Medicine, Yorkshire Ambulance Service NHS Trust, West Yorkshire, GBR.
Bonaventure M OgbodoMorbid Anatomy, University of Nigeria Teaching Hospital, Enugu, NGA.
Olutomiwa OmokoreInternal Medicine, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
Kenelumchukwu EkezieSurgery, The Chiltern Hospital, Great Missenden, GBR.
Obioma AririsukwuMedicine, St. Francois Medical Centre, Abuja, NGA.
Eberechuckwu OnyemachiFamily Medicine, Federal Medical Centre (FMC), Umuahia, Umuahia, NGA.
Nwora OliPediatrics, Nottingham University Hospitals NHS Trust, Nottingham, GBR.
Onyebuchukwu EkeOncology/Toxicology, Nigeria Police Directorate of Medical Services, Abuja, NGA.
Cyprian OkoronkwoInternal Medicine, King Fahad Specialist Hospital, Tabuk, SAU.
Odutola OdugbemiObstetrics and Gynecology, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
Joshua OdeyinkaSurgery, Babcock University Teaching Hospital, Ilishan-Remo, NGA.
Esosa ImafidonSurgery, Babcock University Teaching Hospital, Ilishan-Remo, NGA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mixed germ cell tumours (GCTs) are a rare pathology, particularly those comprising yolk sac tumour (YST) and mature cystic teratomas. Although one important biomarker for YSTs is alpha-fetoprotein (AFP), which is often characteristically elevated, this may not be the case in a minority of cases. Additionally, AFP is not usually elevated in mixed GCTs, more so in cases involving mature cystic teratoma, even with YST as a component of the tumour, as seen in the index patient who had a normal AFB value of 5 ng/mL (normal: 0-10 ng/mL). Furthermore, in postmenopausal women with stage 1 mixed GCTs, the preferred treatment is non-fertility-sparing surgery without chemotherapy. Despite the generally poor prognosis for GCTs in this demographic, early detection and treatment can lead to favourable outcomes. This report details a case of a 58-year-old woman with a stage 1 mixed GCT who underwent extensive surgery without chemotherapy and has remained tumour-free for 24 months, attributing her good prognosis to the low stage and early intervention, along with the YST component.

Indexed as

alpha-feto proteinmature cystic teratomamixed germ cell tumorspostmenopausaltreatmentyolk sac tumor

Identifiers

PMID42317923
PMCPMC13273489

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.