ArticleCureus2026
Bacterial, Antimicrobial, and Clinical Profile of Multidrug-Resistant Gram-Negative Bacilli Isolates From Intensive Care Unit Patients.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Background Multidrug-resistant (MDR) Gram-negative bacilli (GNB) are a major cause of healthcare-associated infections in intensive care units (ICUs), leading to increased morbidity, mortality, and limited treatment options. This study was conducted to determine the prevalence of MDR-GNB among ICU clinical specimens and to evaluate their antimicrobial susceptibility patterns. Material and methods This cross-sectional observational study was carried out at the Department of Microbiology, Krishna Institute of Medical Sciences, Karad, from August 2024 to March 2025. A total of 370 clinical specimens obtained from ICU patients were processed using standard microbiological methods. The VITEK 2 compact automated system (Marcy-l'Étoile, France: bioMérieux) was used to identify Gram-negative bacilli, and VITEK 2 AST cards were used for antibiotic susceptibility testing. Multidrug-resistant isolates were defined as resistance to three or more antimicrobial classes. Results A total of 370 specimens were processed; growth was observed in 228 specimens. Among these, 109 were Gram-positive, and 119 were Gram-negative. Multidrug-resistant Gram-negative bacteria were identified in 101 isolates. The highest burden of infection was observed in both the 31-40 year and 41-50 year age groups, with each group contributing 26 cases (25.74%). Males were more frequently affected than females, contributing 69 (68.32%) cases compared to 32 (31.68%). Among the pathogens,
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