ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2026
KRAS Clinical Trial Finder: A Patient-Centered Platform for Improving Access to Clinical Trial Information.
Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
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Abstract
KRAS mutations are linked to aggressive cancers, yet many patients struggle to locate trials that match their tumor subtype or circumstances. This study presents the design and user-centered evaluation of the KRAS Clinical Trial Finder, a patient-centered platform that improves access to KRAS-specific clinical trial information. A Python pipeline was developed to extract and transform KRAS-related trials from ClinicalTrials.gov into a relational database, which was presented through an interactive R Shiny dashboard offering plain-language summaries and distance calculations. Twenty-eight KRAS Kickers patients and care partners completed four usability tasks, evaluated with the Single Ease Question (SEQ) and System Usability Scale (SUS). Results demonstrated excellent usability (mean SEQ 6.44/7; SUS 91.4) and rapid task completion (mean 66.5 seconds), with 95% expressing willingness to reuse the system. Qualitative analysis identified five improvement domains: visibility, personalization, education, empowerment, and accessibility. Future directions include EHR integration, AI-enabled trial matching, enhanced education, and multilingual support.
Identifiers
42317852PMC13274327What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.