Evidence map›Paper›PMID 42317787›Full record

ArticleRespiratory medicine case reports2026

Long-term CPAP treatment for OSA in pycnodysostosis: A 15-year longitudinal follow-up of a patient.

Abir Bouhamdi, Yassin Chefchaou, Meryem Benjelloun, Sanae Labyad, Abdellah Abida, Zouhayr Souirti, Sana Abourazzak, Siham Tizniti, Mounia Serraj, Bouchra Amara and 2 more

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In one paragraph

Article in Respiratory medicine case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Abir BouhamdiSleep Medicine Center, Hassan II University Hospital, Epidemiology and Health Sciences Research Laboratory, Sidi Mohamed Ben Abdellah University, PO Box: 1835, Route Sidi Harazem, Fez, 30050, Morocco.
Yassin ChefchaouSleep Medicine Center, Hassan II University Hospital, Epidemiology and Health Sciences Research Laboratory, Sidi Mohamed Ben Abdellah University, PO Box: 1835, Route Sidi Harazem, Fez, 30050, Morocco.
Meryem BenjellounSleep Medicine Center, Hassan II University Hospital, Epidemiology and Health Sciences Research Laboratory, Sidi Mohamed Ben Abdellah University, PO Box: 1835, Route Sidi Harazem, Fez, 30050, Morocco.
Sanae LabyadSleep Medicine Center, Hassan II University Hospital, Epidemiology and Health Sciences Research Laboratory, Sidi Mohamed Ben Abdellah University, PO Box: 1835, Route Sidi Harazem, Fez, 30050, Morocco.
Abdellah AbidaSleep Medicine Center, Hassan II University Hospital, Epidemiology and Health Sciences Research Laboratory, Sidi Mohamed Ben Abdellah University, PO Box: 1835, Route Sidi Harazem, Fez, 30050, Morocco.
Zouhayr SouirtiSleep Medicine Center, Hassan II University Hospital, Epidemiology and Health Sciences Research Laboratory, Sidi Mohamed Ben Abdellah University, PO Box: 1835, Route Sidi Harazem, Fez, 30050, Morocco.
Sana AbourazzakDepartment of Pediatrics, Hassan II University Hospital, Sidi Mohamed Ben Abdellah University, PO Box: 1835, Route Sidi Harazem, Fez, 30050, Morocco.
Siham TiznitiDepartment of Radiology, PolyClinique Annakhil, Fez, Morocco.
Mounia SerrajDepartment of Pulmonology, Hassan II University Hospital, Epidemiology and Health Sciences Research Laboratory, Sidi Mohamed Ben Abdellah University, PO Box: 1835, Route Sidi Harazem, Fez, 30050, Morocco.
Bouchra AmaraDepartment of Pulmonology, Hassan II University Hospital, Epidemiology and Health Sciences Research Laboratory, Sidi Mohamed Ben Abdellah University, PO Box: 1835, Route Sidi Harazem, Fez, 30050, Morocco.
Mohamed Chakib BenjellounDepartment of Pulmonology, Hassan II University Hospital, Epidemiology and Health Sciences Research Laboratory, Sidi Mohamed Ben Abdellah University, PO Box: 1835, Route Sidi Harazem, Fez, 30050, Morocco.
Mohammed ElbiazeSleep Medicine Center, Hassan II University Hospital, Epidemiology and Health Sciences Research Laboratory, Sidi Mohamed Ben Abdellah University, PO Box: 1835, Route Sidi Harazem, Fez, 30050, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pycnodysostosis is a rare genetic disorder associated with craniofacial anomalies that promote the occurrence of obstructive sleep apnea (OSA). We report the 15-year longitudinal follow-up of a patient with severe OSA treated with continuous positive airway pressure (CPAP). From the age of 2 years, the patient presented severe OSA confirmed by polysomnography and CPAP was initiated. Throughout follow-up, adherence was excellent (≥90%). Despite multidisciplinary follow-up and the addition of a dental prosthesis aimed at targeted expansion of the oral cavity, persistent maxillo-mandibular retrognathia was still present at age 17 years along with OSA persistence. This case highlights the importance of early and periodic follow-up and evaluation of alternative therapeutic approaches to improve upper airway patency in children with craniofacial syndromes such as pycnodysostosis.

Indexed as

Continuous positive airway pressureLongitudinal follow-upObstructive sleep apneaOrthodonticsPycnodysostosis

Identifiers

PMID42317787
PMCPMC13273886

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.