Evidence map›Paper›PMID 42317778›Full record

ArticleOphthalmology science2026

Pediatric Ebola Eye Disease in the PREVAIL (Partnership for Research on Ebola Virus in Liberia) III Longitudinal Cohort Study.

Rhea Kulkarni, Nii Quartey-Papafio, Jemma Larbelee, Fred Amegashie, Robert Dolo, Catherine Gaisie, Catherine Gargu, Augustine Wallace, Anshuman Agrawal, Mosoka P Fallah and 9 more

Abstract read
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In one paragraph

Article in Ophthalmology science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Rhea KulkarniKansas City University College of Medicine and Biosciences, Kansas City, Missouri.
Nii Quartey-PapafioDana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore.
Jemma LarbeleeRedemption Hospital, Monrovia, Liberia.
Fred AmegashieMinistry of Health, Monrovia, Liberia.
Robert DoloNew Sight Eye Centre, Monrovia, Liberia.
Catherine GaisieKarish Eye Care, Monrovia, Liberia.
Catherine GarguPartnership for Research on Vaccines and Infectious Diseases in Liberia (PREVAIL).
Augustine WallacePartnership for Research on Vaccines and Infectious Diseases in Liberia (PREVAIL).
Anshuman AgrawalDana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore.
Mosoka P FallahPartnership for Research on Vaccines and Infectious Diseases in Liberia (PREVAIL).
J Soka MosesPartnership for Research on Vaccines and Infectious Diseases in Liberia (PREVAIL).
Katrina HarperDepartment of Biostatistics, University of Minnesota, Minneapolis, Minnesota.
Collin Van RynDepartment of Biostatistics, University of Minnesota, Minneapolis, Minnesota.
Cavan ReillyDepartment of Biostatistics, University of Minnesota, Minneapolis, Minnesota.
J Daniel KellyDepartment of Medicine, University of California San Francisco, San Francisco, California.
Rachel J BishopDana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore.
Allen O EghrariDana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore.
S Grace PrakalapakornDepartment of Ophthalmology, Duke University Medical Center, Durham, North Carolina.
PREVAIL III Eye Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Ebola virus disease (EVD) is associated with vision-threatening ophthalmic sequelae, yet outcomes in young survivors remain poorly characterized. We sought to distinguish ophthalmic pathology in pediatric EVD survivors relative to close contacts and adult EVD survivors. Design: Cross-sectional baseline analysis of participants enrolled in the Partnership for Research on Ebola Virus in Liberia (PREVAIL) III longitudinal cohort study. Participants: Eighty-eight pediatric EVD survivors (ages 6-17 years), 203 pediatric close contacts (ages 6-17 years), and 463 adult EVD survivors (ages ≥18 years). Testing: Visual function testing, slit-lamp biomicroscopy, indirect ophthalmoscopy, and OCT. Main Outcome Measures: Prevalence of ocular symptoms, functional vision measures, and evidence of inflammation on examination and imaging. Results: Compared with close contacts, pediatric EVD survivors at their baseline visit experienced significantly higher rates of light sensitivity (43.2% vs. 31.2%, Conclusions: Pediatric EVD survivors exhibit a distinct profile of ocular sequelae compared with both close contacts and adult survivors, characterized by higher rates of anterior segment inflammation. These findings highlight the importance of considering the unique needs of children in the setting of emerging infectious diseases. Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

Indexed as

Anterior segmentEbola virus diseaseEVDPediatricUveitis

Identifiers

PMID42317778
PMCPMC13273659

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.