ArticleFrontiers in pediatrics2026
Health-related quality of life and its determinants in children with allergic rhinitis.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Allergic rhinitis (AR) is highly prevalent in school-aged children and can substantially impair health-related quality of life (HRQoL). The modifiable determinants of HRQoL in this population remain incompletely understood. Methods: In this cross-sectional study, 110 children aged 6-12 years with physician-diagnosed AR and 110 age- and sex-matched healthy controls were enrolled from a tertiary hospital (January-December 2023). HRQoL was assessed using the Pediatric Rhinoconjunctivitis Quality of Life Questionnaire (PRQLQ). A visual analog scale (VAS) quantified four core nose symptoms, while a structured questionnaire captured household environmental exposures, allergen patterns, and treatment adherence. Anxiety and sleep quality were evaluated using HADS-A and PSQI, respectively. Independent-samples t tests, repeated-measures ANOVA with Bonferroni correction, and multiple linear regression were performed. Results: The Chinese PRQLQ demonstrated good reliability, with an overall Cronbach's Conclusions: AR markedly impairs HRQoL in school-aged children. Targeted management of nose symptoms, household exposures, adherence, and psychosocial factors, combined with timely allergen immunotherapy, may optimize quality of life.
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