Evidence map›Paper›PMID 42317626›Full record

ArticleData in brief2026

Dataset of illicit drug consumption during and post COVID-19 through wastewater in a city of Chile.

Andressa S Reis, Francisca Corthorn, Patricio Navarro, Paulina Assmann, Eduardo Suazo Osses, Matias I Hepp, Cristóbal Galbán-Malagón

Abstract read
In one paragraph

Article in Data in brief, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andressa S ReisInstituto de Ciencias Naturales, Facultad Medicina Veterinaria y Agronomía, Universidad de Las Américas, Av. Pdte., Jorge Alessandri Rodriguez 1160, Concepción, Región del Biobío, Chile.
Francisca CorthornCentro Latinoamericano de Investigación de Aguas Residuales, Av. del Parque 4980, Huechuraba, Región Metropolitana, Santiago, Chile.
Patricio NavarroSustancias Químicas Controladas, Policía De Investigaciones de Chile, General Borgoño 1204, Piso 7, Santiago, Región Metropolitana, Santiago, Chile.
Paulina AssmannDepartamento de Físicas, Facultad de Físicas y Matemáticas, Universidad de Concepción, Av. Esteban S. Iturra, Concepción, Región del Biobío, Chile.
Eduardo Suazo OssesCentro de Vigilancia de Aguas Residuales, Centinela Biobío, Facultad de Medicina, Universidad Católica de La Santísima Concepción, Av. Alonso de Ribera 2850, Concepción, Región del Biobío, Chile.
Matias I HeppCentro de Vigilancia de Aguas Residuales, Centinela Biobío, Facultad de Medicina, Universidad Católica de La Santísima Concepción, Av. Alonso de Ribera 2850, Concepción, Región del Biobío, Chile.
Cristóbal Galbán-MalagónCentro de Genómica Ecología y Medio ambiente (GEMA), Universidad Mayor, Camino La Pirámide 5750, Santiago, Huechuraba, Región Metropolitana, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present dataset reports illicit drug consumption estimated through wastewater-based epidemiology (WBE) in San Pedro de la Paz, Biobío Region, Chile. We collected 24 hour flow proportional Influent wastewater samples at the city wastewater treatment plant (WWTP). Sampling during the COVID-19 period was conducted on twelve days between 9 and 29 August 2021. We collected 50 samples divided in two periods i) COVID-19 period (between 9 and 29 August 2021) and ii) Post-COVID-19 (5 September 2022 to 30 August 2023). Samples collected were preserved by adding Sodium metabisulfite (0.5 g/L), and samples were stored at -20 °C until further analysis. Target analytes included benzoylecgonine (cocaine metabolite), 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THCCOOH, cannabis metabolite), amphetamine, and 3,4-methylenedioxymethamphetamine (MDMA). Sample preparation involved filtration, pH adjustment, and solid-phase extraction, followed by quantitative analysis using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Quality assurance and quality control (QA/QC) followed the best-practice protocols of the Sewage CORe Group Europe (SCORE) network, including isotopically labelled internal standards, matrix-matched calibration, recovery and matrix-effect assessment, and batch-level blanks and continuing calibration verifications. We normalized concentrations using the daily influent flow and estimated population served by the wastewater treatment plant according to the 2024 Chilean CENSUS. Results are reported as milligrams per day per 1000 inhabitants (mg/day/1000 inhabitants), with values below the limit of quantification informed as "NA". We provide the dataset in an excel file containing collection date, location information, population data, and normalized consumption estimates for each target compound. Data are publicly available in the Mendeley Data repository (DOI: 10.17632/vgpr6b99vf.1) and can be reused for methodological comparisons, inter-study analyses, and secondary modeling applications in WBE.

Indexed as

AmphetamineCannabisCocaineIllicit drugsMDMAWastewater-based epidemiology

Identifiers

PMID42317626
PMCPMC13273887

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.