Evidence map›Paper›PMID 42317395›Full record

ArticleEuropean heart journal. Imaging methods and practice2026

AI as a peer reviewer: a blinded comparative study of LLM-generated and human reviews in a cardiology journal.

Edoardo Zancanaro, Andreas Giannopoulos, Alessia Gimelli, Karl-Patrik Kresoja

Abstract read
In one paragraph

Article in European heart journal. Imaging methods and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. AI as a peer reviewer: who and how evaluate manuscript value?European heart journal. Imaging methods and practice · 2026
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Edoardo ZancanaroBrigham and Women's Hospital, Harvard Medical School, 45 st francis st., Boston, MA 02115, USA.ORCID https://orcid.org/0000-0003-0259-0844
Andreas GiannopoulosDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Zürich, Switzerland.
Alessia GimelliImaging Department, Fondazione CNR-Regione Toscana 'Gabriele Monasterio', Pisa, Italy.
Karl-Patrik KresojaDepartment of Cardiology, Cardiology I, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Peer review is a cornerstone of scientific quality control, yet it is increasingly burdened by growing manuscript volumes and reviewer fatigue. Large language models (LLMs) have emerged as potential tools to support scientific review, but it remains unclear whether AI-generated reviews are equivalent to human reviews on the endpoint that ultimately matters, agreement with the final editorial decision. Methods and results: We retrieved 40 manuscripts previously submitted to a cardiology journal (20 ultimately accepted, 20 Conclusion: LLM-generated peer reviews are non-inferior to human reviews in terms of agreement with the final editorial decision, while showing higher internal consistency, comparable quality on structured domains, and substantially shorter turnaround. These findings support the integration of AI as a complementary tool in editorial workflows, rather than as a replacement for human peer review.

Indexed as

artificial intelligencecardiologyeditorial decisionlarge language modelspeer review

Identifiers

PMID42317395
PMCPMC13274465

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.