Evidence map›Paper›PMID 42317282›Full record

ArticleEJHaem2026

Diagnosing and Managing Paradoxical Deep Vein Thrombosis in a Patient With Congenital Afibrinogenemia.

Altamash Jawadi, Malik Alqawasmi, Mahmoud Abdelsamia, Hemza Assed, Mohammad Adawee, Mohammad Badawy, Xuan Thuy T Nguyen, Andres E Mindiola Romero, Allison Burnett, Ala Ebaid

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJHaem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Altamash JawadiDepartment of Internal Medicine The University of New Mexico Albuquerque New Mexico USA.
Malik AlqawasmiDepartment of Internal Medicine The University of New Mexico Albuquerque New Mexico USA.
Mahmoud AbdelsamiaDivision of Hematology/Oncology The University of New Mexico Cancer Comprehensive Center Albuquerque New Mexico USA.
Hemza AssedSchool of Medicine The University of New Mexico Albuquerque New Mexico USA.
Mohammad AdaweeSchool of Medicine The University of New Mexico Albuquerque New Mexico USA.
Mohammad BadawySchool of Medicine The University of New Mexico Albuquerque New Mexico USA.
Xuan Thuy T NguyenDepartment of Internal Medicine The University of New Mexico Albuquerque New Mexico USA.
Andres E Mindiola RomeroDepartment of Pathology The University of New Mexico Albuquerque New Mexico USA.
Allison BurnettAntithrombosis Stewardship Pharmacy The University of New Mexico Albuquerque New Mexico USA.
Ala EbaidDivision of Hematology/Oncology The University of New Mexico Cancer Comprehensive Center Albuquerque New Mexico USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital afibrinogenemia, classically a bleeding disorder, can paradoxically predispose to thrombosis, potentially due to disruptions in fibrin-mediated thrombin clearance and plasmin activation. A young man with reported congenital afibrinogenemia presented with extensive deep vein thrombosis in the setting of undetectable fibrinogen and deceptively low D-dimer, revealing the limitations of fibrin-dependent assays. Management required carefully balanced anticoagulation alongside fibrinogen replacement with subsequent genetic confirmation of a homozygous

Indexed as

congenital afibrinogenemiaD‐dimerdeep vein thrombosisfibrinogen replacement therapyinherited fibrinogen disorders

Identifiers

PMID42317282
PMCPMC13273846

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.