Trial reportJournal of genetic counseling2026
The effects of mindfulness meditation on burnout in clinical genetic counselors: A three-arm randomized controlled trial.
Trial report in Journal of genetic counseling, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Burnout is common among genetic counselors (GCs). Clinician burnout has been found to adversely affect individual well-being, patient care, and the likelihood of staying in a role. Both individual and system-level solutions are needed to address burnout. Mindfulness meditation (MM) is one individual-level solution that has shown promise for reducing burnout in clinicians, but has not been studied in GCs. We conducted a decentralized, parallel, three-arm randomized controlled trial comparing MM to a novel active control meditation (ACM) and a no-meditation control (NMC), with 1:1:1 randomization. Participants were clinical GCs in the United States. MM and ACM participants were asked to do 10 min of daily app-based meditation for 8 weeks. ACM was designed to control for nonspecific aspects of MM by mimicking MM length and structure without including mindfulness techniques. The primary outcome, burnout, was assessed using the Professional Fulfillment Index. Secondary outcomes included other indicators of professional well-being, such as stress and professional fulfillment. Outcomes were assessed via an intention-to-treat approach, with multiple imputation for missing outcome data. Outcome analyses controlled for baseline trait mindfulness. Three hundred and ninety-seven participants (median age 31 years; 97.7% female, 94.2% White) were randomized, and 76% completed post-intervention outcome measures. At baseline 57% of GCs met criteria for burnout. There was no difference in burnout reduction between MM and ACM groups (p = 0.53). However, multiple measures suggest that ACM did not perform well as an active meditation control, thus the primary hypothesis could not be effectively tested. In prespecified secondary analyses, MM reduced burnout (Cohen's d = -0.84, p < 0.001) compared to NMC, a passive control. Similar results were seen for stress. These findings suggest MM may be beneficial for GC professional well-being; however, further research on MM for GCs is needed with more diverse study samples and better active controls.
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