Evidence map›Paper›PMID 42316947›Full record

ArticleAdvanced healthcare materials2026

Synergistic Immunomodulation and Angiogenesis-Driven Microenvironment Remodeling via Bioactive Hydrogel/Nanofiber Composites for Enhanced Infectious Wound Healing.

Ziyi Zhou, Dengjun Zhang, Qingxia Guo, Linbo Jin, Yuanfei Wang, Jiaping Zhang, Tong Wu, Yiming Zhang

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ziyi ZhouDepartment of Plastic and Cosmetic Surgery, Xinqiao Hospital, Army Medical University, Chongqing, China.
Dengjun ZhangDepartment of Plastic and Cosmetic Surgery, Xinqiao Hospital, Army Medical University, Chongqing, China.
Qingxia GuoMedical Research Center, The Affiliated Hospital of Qingdao University, Qingdao Medical College, Qingdao University, Qingdao, China.
Linbo JinDepartment of Plastic and Cosmetic Surgery, Xinqiao Hospital, Army Medical University, Chongqing, China.
Yuanfei WangMedical Research Center, The Affiliated Hospital of Qingdao University, Qingdao Medical College, Qingdao University, Qingdao, China.
Jiaping ZhangDepartment of Plastic Surgery, State Key Laboratory of Trauma, Burns and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.ORCID https://orcid.org/0000-0003-4034-883X
Tong WuMedical Research Center, The Affiliated Hospital of Qingdao University, Qingdao Medical College, Qingdao University, Qingdao, China.ORCID https://orcid.org/0000-0001-8822-1868
Yiming ZhangDepartment of Plastic and Cosmetic Surgery, Xinqiao Hospital, Army Medical University, Chongqing, China.ORCID https://orcid.org/0000-0003-1000-9108

Funding

Chongqing Natural Science Foundation CSTB2024NSCQ-MSX0538Textile Vision Basic Research Program of China National Textile and Apparel Council J202404
6 · The paper itself

Abstract

Numerous types of wounds are at risk for infection, such as burn wounds, traumatic wounds, surgical wounds, chronic ulcer wounds, and radiologic wounds. The repair of infectious wounds depends on specific microenvironments, including moderate hydration, reactive oxygen scavenging, antimicrobial, anti-inflammatory, and angiogenic conditions. To effectively promote the repair of infectious wounds and reduce the risk of infection spread, we developed a multifunctional bilayer wound dressing (MBWD) that simultaneously meets these criteria. The inner layer (DMOG@PCL/ASC) consists of a polycaprolactone (PCL)/fish collagen (ASC) nanofiber decorated with coaxial microparticles containing dimethyloxalylgcine (DMOG). The three-dimensional pore structure of nanofibers offers numerous adhesion sites for cells, and the gradual release of DMOG can promote angiogenesis. The outer layer consists of a glycidyl methacrylate-modified carboxymethyl chitosan hydrogel loaded with cerium oxide nanozymes (M-CMCS/CeO

Indexed as

HydrogelsImmunomodulationNanofibersNeovascularization, PhysiologicWound HealingWound InfectionAnimalsBandagesCellular MicroenvironmentCeriumCollagenHumansMaleMicePolyestersceric oxideCeriumCollagenHydrogelspolycaprolactonePolyestersangiogenesishydrogelimmunomodulationinfectious woundsnanofibers

Identifiers

PMID42316947
PMCPMC13378487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.