Evidence map›Paper›PMID 42316809›Full record

ReviewDevelopmental medicine and child neurology2026

Migraine in children and adolescents.

Ishaq Abu-Arafeh

Abstract readReview
In one paragraph

Review in Developmental medicine and child neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ishaq Abu-ArafehPaediatric Neurosciences Unit, Royal Hospital for Children, Glasgow, UK.ORCID https://orcid.org/0000-0003-1252-0153

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This narrative review explores recent advances in the study of migraine with an emphasis on its complex polygenic aetiology, pathogenesis, clinical presentation, and the potential for new specific mechanism-based treatments in children and adolescents. The polygenic aetiology and complex pathogenesis of migraine make its clinical presentation subject to the influences of intrinsic physiological and psychological factors as well as extrinsic environmental and lifestyle factors. In addition to variation in the clinical presentation of migraine in children, several disorders, such as abdominal migraine, cyclical vomiting syndrome, benign paroxysmal vertigo, benign paroxysmal torticollis, and infantile colic, are considered under the wide umbrella of childhood migraine syndrome. Advances in the study of migraine pathophysiology have identified the important roles of several neurotransmitters and opened the way for the development of new specific medication to treat migraine episodes and for prevention. In the absence of reliable biomarkers, clinical assessment remains the backbone for the diagnosis and assessment of migraine. With better understanding of the complexity of migraine pathophysiology comes the realization that no single drug will solve all the problems of the disease for all patients.

Indexed as

Migraine DisordersAdolescentChildHumans

Identifiers

PMID42316809
PMCPMC13545486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.