Evidence map›Paper›PMID 42316520›Full record

ReviewThe Korean journal of helicobacter and upper gastrointestinal research2026

Pharmacological Management of Peptic Ulcer Bleeding.

Hannah Lee, Jun-Won Chung, Kyoung Oh Kim, Kwang An Kwon, Jung Ho Kim

Abstract readReview
In one paragraph

Review in The Korean journal of helicobacter and upper gastrointestinal research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hannah LeeDivision of Gastroenterology, Department of Internal Medicine, Gachon University Gil Medical Center, College of Medicine, Gachon University, Incheon, Korea.
Jun-Won ChungDivision of Gastroenterology, Department of Internal Medicine, Gachon University Gil Medical Center, College of Medicine, Gachon University, Incheon, Korea. junwonchung@daum.net.
Kyoung Oh KimDivision of Gastroenterology, Department of Internal Medicine, Gachon University Gil Medical Center, College of Medicine, Gachon University, Incheon, Korea.
Kwang An KwonDivision of Gastroenterology, Department of Internal Medicine, Gachon University Gil Medical Center, College of Medicine, Gachon University, Incheon, Korea.
Jung Ho KimDivision of Gastroenterology, Department of Internal Medicine, Gachon University Gil Medical Center, College of Medicine, Gachon University, Incheon, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptic ulcer bleeding (PUB) is the most common cause of non-variceal upper gastrointestinal bleeding, although its incidence is decreasing worldwide. Current epidemiological evidence demonstrates the positive influence of Helicobacter pylori eradication on outcomes, owing to the widespread introduction of proton pump inhibitor (PPI) treatment. However, PUB is still commonly encountered in clinical settings given the increasing indications for nonsteroidal anti-inflammatory drugs, anticoagulants, and antiplatelet agents in the aging population. Regardless of advancements made in the endoscopic approach and pharmacological treatment, upper gastrointestinal bleeding has an inevitable mortality rate ranging from 7% to 11%. Endoscopic treatment is recommended for peptic ulcers with current bleeding, vessel exposure, or clotting. However, the development of effective high-dose PPIs has resulted in a decrease in rebleeding events after endoscopic treatment. Pharmacological management consisting of post-endoscopic treatment was more effective than pre-endoscopic treatment. As PPIs ensure that gastric acidity remains above pH 6, they are essential treatments for PUB. This review aimed to investigate the current strategies for PUB pharmacological management.

Indexed as

Peptic ulcerPharmacologyUpper gastrointestinal tract

Identifiers

PMID42316520
PMCPMC13284566

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.