Trial reportHuman brain mapping2026
Interhemispheric Metabolic Effects of Transcranial Infrared Laser Stimulation of the Prefrontal Cortex.
Trial report in Human brain mapping, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Photobiomodulation is the use of low-power, non-ionizing light to stimulate cellular processes. Transcranial infrared laser stimulation (TILS) is a method for prefrontal photobiomodulation that produces dose-dependent metabolic effects in vivo. However, interhemispheric differences in metabolic responses to unilateral right versus left TILS are unknown. Investigating interhemispheric effects of TILS is important because right-left differences are observed with other forms of transcranial stimulation, including magnetic and electrical stimulation. TILS penetration was first characterized using Monte Carlo simulations of photon propagation in the Colin27 MRI-based brain model. Simulations confirmed that 1%-5% photon penetration was confined unilaterally to the stimulated side of the prefrontal cortex. Eighty-one healthy adults were then randomized to receive unilateral right TILS, unilateral left TILS, or sham stimulation (laser off). Active TILS parameters were selected based on prior studies demonstrating metabolic efficacy (1064 nm continuous wave, 250 mW/cm
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