Evidence map›Paper›PMID 42316391›Full record

ArticleAdvanced healthcare materials2026

Engineered AuNPs/fMWCNT Nanocomposite Electrodes for High-Sensitivity Methylglyoxal Sensing in Saliva and Sweat for Non-Invasive Diabetes Monitoring.

Ahadul Amin Soshi, Md Younus Ali, Dadbeh Pazuki, Matiar M R Howlader

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ahadul Amin SoshiDepartment of Electrical and Computer Engineering, McMaster University, Hamilton, Canada.
Md Younus AliDepartment of Electrical and Computer Engineering, McMaster University, Hamilton, Canada.
Dadbeh PazukiDepartment of Electrical and Computer Engineering, McMaster University, Hamilton, Canada.
Matiar M R HowladerDepartment of Electrical and Computer Engineering, McMaster University, Hamilton, Canada.

Funding

McMaster Start-up GrantMcMaster University Faculty of Engineering Doctoral Scholarship for Multi-Disciplinary Research AwardNatural Science and Engineering Research Council RGPIN-2024-06809
6 · The paper itself

Abstract

Elevated methylglyoxal (MG) levels contribute to diabetes-related complications through accelerated formation of advanced glycation end products, highlighting the need for sensitive, portable, and non-invasive monitoring strategies. Here, we report a gold-carbon nanohybrid electrochemical MG sensor integrated into a three-dimensional printed microfluidic platform for point-of-care analysis. The sensing interface is engineered by sequential electrodeposition of carboxyl-functionalized multi-walled carbon nanotubes (fMWCNT) and gold nanoparticles (AuNPs) onto a screen-printed carbon electrode (SPCE). The fMWCNT provide a high-surface-area scaffold for MG adsorption, while AuNPs enhance electroactive surface area and electron transfer. The AuNPs/fMWCNT/SPCE sensor exhibits quasi-reversible electrochemical behavior suitable for sensitive MG detection. The optimized sensor achieves reliable MG detection across a wide dynamic range (50 nM-100 µM), with limits of detection of 40 nM in aqueous media and 400 nM in artificial sweat. Accurate MG quantification in human saliva and sweat, with recoveries exceeding 97%, demonstrates robustness in complex biological matrices. This work demonstrates the potential of this electrochemical sensing system for future wearable biosensors and personalized diabetes monitoring.

Indexed as

Diabetes MellitusGoldMetal NanoparticlesNanocompositesNanotubes, CarbonPyruvaldehydeSalivaSweatBiosensing TechniquesElectrochemical TechniquesElectrodesHumansGoldNanotubes, CarbonPyruvaldehydecarbon nanotubesdiabeteselectrochemical sensorelectrodepositiongold nanoparticlesmethylglyoxalmicrofluidic device

Identifiers

PMID42316391
PMCPMC13410462

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.