Evidence map›Paper›PMID 42316280›Full record

ArticleAdvanced healthcare materials2026

Chemotactic Gold Nanozyme-Powered Flasklike Pentosan Nanobots for Tumor-Specific Drug Delivery.

Qinqin Ruan, Meng Mao, Qiang He, Yingjie Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qinqin RuanSchool of Medicine and Health, Harbin Institute of Technology, Harbin, China.
Meng MaoSchool of Medicine and Health, Harbin Institute of Technology, Harbin, China.
Qiang HeSchool of Medicine and Health, Harbin Institute of Technology, Harbin, China.ORCID https://orcid.org/0000-0002-3557-6865
Yingjie WuSchool of Medicine and Health, Harbin Institute of Technology, Harbin, China.ORCID https://orcid.org/0000-0003-2480-257X

Funding

National Natural Science Foundation of China 22193033National Natural Science Foundation of China U23A20342
6 · The paper itself

Abstract

Enzyme-powered nanobots represent a promising strategy for active and targeted drug delivery due to their autonomous propulsion and directional motion. However, the instability and environmental vulnerability of natural enzymes severely compromise their functionality in the tumor microenvironment (TME). Herein, we report a chemotactic nanobot system powered by gold nanozymes and constructed within a flasklike pentosan architecture for tumor-specific drug delivery. Benefiting from the intrinsic glucose oxidase-like and peroxidase-like activities of gold nanozymes, these nanobots exploit endogenous glucose and elevated hydrogen peroxide (H

Indexed as

ChemotaxisDrug Delivery SystemsGoldMetal NanoparticlesNeoplasmsAnimalsCell Line, TumorDoxorubicinGlucose OxidaseHumansHydrogen PeroxideMiceTumor MicroenvironmentDoxorubicinGlucose OxidaseGoldHydrogen Peroxidechemotaxisnanobotnanozyme‐poweredtargeted deliverytumor microenvironment

Identifiers

PMID42316280
PMCPMC13411039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.