ArticleBMC surgery2026
Prognostic value of hematological markers for anastomotic leakage diagnosed after postoperative day 5 following laparoscopic surgery for colorectal cancer.
Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundAnastomotic leakage (AL) is a common complication following colorectal cancer surgery, yet accurate and unified diagnostic criteria remain lacking.
methodsThis retrospective study included 360 patients who underwent laparoscopic colorectal resection with one-stage anastomosis at the First Affiliated Hospital of Kunming Medical University between October 2019 to December 2023. Hematocrit-to-albumin difference (HCT-ALB), neutrophil-to-albumin ratio (NAR), and neutrophil-to-lymphocyte ratio (NLR) on postoperative days (POD) 1, 3, and 5 were compared between patients with and without AL. This study specifically aimed to evaluate the predictive performance of these markers for AL occurring after POD 5.
resultsCompared to the non-AL group, the AL group exhibited significantly higher HCT-ALB, NAR, and NLR values on POD 3 and 5 (P < 0.05), except for NLR on POD 1. Multivariate analysis identified rectal tumor location, HCT-ALB and NLR on POD 3, and NAR and NLR on POD 5 as associated factors of AL, while preoperative ALB, HCT-ALB on POD1 and POD5, and NAR on POD1 and POD3 showed weaker associations (P > 0.05). The best predictors were NAR on POD 5 (AUC = 0.910, cut-off = 2.09) and NLR on POD 5 (AUC = 0.885, cut-off = 7.19). Due to the exploratory nature of this study and the potential for collinearity between these inflammatory markers, these results should be interpreted with caution.
conclusionTumor location (rectum), HCT-ALB and NLR on POD 3, and NAR and NLR on POD 5 may serve as reliable indicators for AL, thus enabling early identification and timely intervention to improve postoperative outcomes after colorectal surgery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.