SynthesisBMC pregnancy and childbirth2026
Prevalence of fetal macrosomia and associated factors among delivered neonates in Ethiopia: a systematic review and meta-analysis.
Synthesis in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundGlobally, macrosomia affects 3 to 15% of all pregnancies; there is a global variation in the magnitude of macrosomia among countries. It is one of the public health problems in most developing countries and contributes to maternal and newborn complications. There are some inconsistent individual studies done in Ethiopia, but there is no current pooled national data on its prevalence and factors associated with it. So the study will be used to design and implement a well-comprehensive intervention targeting maternal and child health services.
objectiveTo estimate the pooled prevalence and associated factors of fetal macrosomia in Ethiopia.
methodsA systematic review and Meta-analysis of published and grey literature was conducted. A Web of Science, EMBASE, PubMed, Scopus, African Journals Online and Elsevier Science direct were searched as electronic databases, while Google Scholar was utilized as a supplementary search engine. Joanna Briggs Institute (JBI) quality appraisal tools were used for quality assessment and the study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist to maintain scientific robustness. Statistical analyses were performed using STATA software (version 14). For each identified associated factor, pooled effect sizes, 95% confidence intervals and measures of statistical heterogeneity were calculated. Heterogeneity among the included studies was quantified using I
resultA total of 4309 neonates were delivered in Ethiopian Health institutions, from which 3670 singleton births were included to estimate the pooled effect of fetal macrosomia. The pooled prevalence of fetal macrosomia among delivered neonates in Ethiopia was 10.84% (95% CI: 6.38%-15.31%). Regionally, the highest and lowest pooled estimates were reported from Tigray (13.24%) and Amhara region (7.41%) respectively. Significant heterogeneity was observed across the pooled effect (I
conclusionFetal macrosomia represents a notable public health concern in Ethiopia, with a pooled prevalence exceeding multiple Sub-Saharan regional reports. Because pooled exposure analyses were highly underpowered and statistically non-significant, routine clinical screening during antenatal care should be strengthened, and larger prospective cohort studies are required to establish precise national risk pathways.
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