Evidence map›Paper›PMID 42315845›Full record

ArticleNature communications2026

The hippocampus becomes topographically and functionally specialized along the longitudinal axis with development.

Jonah Kember, Ying He, Zeus Gracia-Tabuenca, Alexander Barnett, Xiaoqian J Chai

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jonah KemberMcGill University, Department of Neurology and Neurosurgery, McGill University, Montréal, QC, Canada. jonah.kember@mail.mcgill.ca.ORCID 0009-0000-3683-3678
Ying HeMcGill University, Department of Neurology and Neurosurgery, McGill University, Montréal, QC, Canada.
Zeus Gracia-TabuencaMcGill University, Department of Neurology and Neurosurgery, McGill University, Montréal, QC, Canada.ORCID 0000-0003-2461-8588
Alexander BarnettMcGill University, Department of Neurology and Neurosurgery, McGill University, Montréal, QC, Canada.ORCID 0000-0001-5891-7880
Xiaoqian J ChaiMcGill University, Department of Neurology and Neurosurgery, McGill University, Montréal, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human hippocampus exhibits distinct genetic, cellular, and connectivity profiles along its anterior-posterior long-axis, resulting in a differential sensitivity to visuospatial information. Long-axis development, therefore, may contribute to developmental increases in visuospatial memory capacity. To test this, we developed and applied a precision functional mapping technique to identify functional systems in the hippocampus of single subjects using BOLD-fMRI (N = 471, aged 5-21). We discovered considerable developmental remodeling of the hippocampal long-axis, particularly for the posterior functional system. With age, surface-area (mm

Indexed as

HippocampusAdolescentBrain MappingChildChild, PreschoolFemaleHumansMagnetic Resonance ImagingMaleMemoryYoung Adult

Identifiers

PMID42315845
PMCPMC13434241

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.