Evidence map›Paper›PMID 42315761›Full record

ReviewArchives of orthopaedic and trauma surgery2026

Surgical treatment of varus unicompartmental knee osteoarthritis: indications, trends, and outcomes-a narrative review.

Carmelo Burgio, Francesco Bosco, Claudio Cobisi, Karlos Zepeda, Fortunato Giustra, Marcello Capella, David Mayman, Eytan Debbi, Jonathan Vigdorchik

Abstract readReview
In one paragraph

Review in Archives of orthopaedic and trauma surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carmelo BurgioAdult Reconstruction and Joint Replacement Service, Hospital for Special Surgery, New York, USA. burgioc@hss.edu.
Francesco BoscoDepartment of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy. francesco.bosco03@unipa.it.
Claudio CobisiDepartment of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.
Karlos ZepedaAdult Reconstruction and Joint Replacement Service, Hospital for Special Surgery, New York, USA.
Fortunato GiustraDepartment of Orthopedics and Traumatology, Ospedale San Giovanni Bosco, Turin, Italy.
Marcello CapellaDepartment of Orthopedic Surgery, CTO Hospital, Turin, Italy.
David MaymanAdult Reconstruction and Joint Replacement Service, Hospital for Special Surgery, New York, USA.
Eytan DebbiAdult Reconstruction and Joint Replacement Service, Hospital for Special Surgery, New York, USA.
Jonathan VigdorchikAdult Reconstruction and Joint Replacement Service, Hospital for Special Surgery, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVarus unicompartmental knee osteoarthritis (UC-KOA) is a frequent and heterogeneous clinical condition characterized by compartment-specific cartilage degeneration and frequently associated with lower-limb malalignment. The progressive understanding of knee biomechanics and alignment has led to the development of surgical strategies specifically tailored to address isolated compartment disease. The purpose of this narrative review is to evaluate indications, current trends, and clinical outcomes of the main surgical options for varus UC-KOA, with particular focus on realignment osteotomies and unicompartmental knee arthroplasty (UKA). MATERIALS AND

methodsA narrative review of the literature was conducted using major biomedical databases. Evidence related to biomechanics, alignment correction, osteotomy techniques, UKA indications, implant evolution, complication profiles, and comparative outcomes was analyzed and synthesized thematically.

resultsBiomechanical and clinical evidence consistently identifies malalignment as a key driver of isolated compartment degeneration. Corrective osteotomies effectively restore physiological load distribution and provide durable outcomes in selected patients with extra-articular deformity. Advances in implant design and surgical techniques have substantially improved UKA survivorship, allowing broader patient selection without compromising clinical outcomes. Comparative studies indicate that osteotomy and UKA serve complementary roles, with specific advantages depending on patient age, activity level, deformity origin, and joint status.

conclusionsCurrent evidence supports an individualized, alignment-based, compartment-specific approach to the surgical management of varus UC-KOA, emphasizing patient-specific decision-making grounded in biomechanical principles.

Indexed as

Arthroplasty, Replacement, KneeOsteoarthritis, KneeOsteotomyBiomechanical PhenomenaHumansTreatment OutcomeAlignmentArthroplastyOsteotomyUKAUnicompartmental

Identifiers

PMID42315761
PMCPMC13279471

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.