SynthesisEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2026
Which diagnostic tools and criteria to use for diagnosis of HSPM and MIH? A systematic review.
Synthesis in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global prevalence of hypomineralised second primary molars: an updated systematic review with a meta-analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo make an overview of the (1) diagnostic tools and (2) diagnostic criteria for MIH and HSPM.
methodsThis systematic review was registered with Prospero (CRD420251146107). Only studies in humans were included. The phenomenon of interest was enamel hypomineralisation, MIH and HSPM, in the primary and permanent dentition. Outcomes of interest were: definition; terminology used; clinical characteristics; radiological; and structural features; patient-reported symptoms; and differential diagnosis. The searches were completed on September 25th 2025 using the following databases: PubMed, Embase, Web of Science, Open Grey, and Cochrane Library. This search gave 2536 articles. After removal of duplicates, 1194 articles were screened for eligibility based on abstracts. Each abstract was rated by one of the reviewers (NS, ICM), in case of disagreement to be discussed among them, and if needed with a third author (ME). For 39 abstracts, the complete article was retrieved and rated. NS and ICM split the amount of articles, and ME assessed half of the articles from both of them as a second check.
resultsThirteen articles were included. There were three articles that compared different indices to diagnose MIH, and five articles on the use of artificial intelligence (AI) in diagnosing MIH. Other papers handled either sensitivity, transillumination, fluorescence, or diagnosis from photographs. The articles on AI had a moderate-to-high risk of bias.
conclusionsThere are few articles on diagnostic tools and diagnostic criteria for HSPM and MIH. The lack of good research on these topics influences the quality of the research in the field of HSPM and MIH.
Indexed as
Identifiers
42315749What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.