Evidence map›Paper›PMID 42315519›Full record

ArticleNature communications2026

The Bacillus subtilis circadian clock coordinates intricate spatiotemporal organisation.

Jack Dorling, Francesca Sartor, Borja Ferrero-Bordera, Edward Godfrey, Zheng Eelderink-Chen, Ella Baker, Isobel K Banks, Akshat Joshipura, Xinming Xu, Romain Avellan and 3 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jack Dorling *Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich, UK.
Francesca Sartor *Institute of Medical Psychology, Faculty of Medicine, University of Munich, Munich, Germany.
Borja Ferrero-BorderaInstitute of Medical Psychology, Faculty of Medicine, University of Munich, Munich, Germany.
Edward GodfreyInstitute of Medical Psychology, Faculty of Medicine, University of Munich, Munich, Germany.
Zheng Eelderink-ChenInstitute of Medical Psychology, Faculty of Medicine, University of Munich, Munich, Germany.
Ella BakerDepartment of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich, UK.ORCID 0000-0002-1812-1033
Isobel K BanksDepartment of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich, UK.ORCID 0009-0001-7774-9832
Akshat JoshipuraInstitute of Medical Psychology, Faculty of Medicine, University of Munich, Munich, Germany.ORCID 0009-0003-5331-9007
Xinming XuInstitute of Biology, Leiden University, Leiden, Netherlands.ORCID 0000-0002-3203-4526
Romain AvellanInstitute of Biology, Leiden University, Leiden, Netherlands.ORCID 0009-0001-3596-653X
Ákos T KovácsInstitute of Biology, Leiden University, Leiden, Netherlands.ORCID 0000-0002-4465-1636
Antony N DoddDepartment of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich, UK. antony.dodd@jic.ac.uk.ORCID 0000-0001-6859-0105
Martha MerrowInstitute of Medical Psychology, Faculty of Medicine, University of Munich, Munich, Germany. martha.merrow@med.uni-muenchen.de.ORCID 0000-0002-8688-2360

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) 507872050EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 101166968
6 · The paper itself

Abstract

Many organisms have circadian clocks that anticipate the risks and benefits of the predictable 24 h solar cycle. However, the potential functions of circadian clocks in non-photosynthetic bacteria are poorly understood. Here, we show that the Bacillus subtilis circadian clock regulates colony expansion, in concert with key developmental and differentiation pathways that are central to its life cycle. The B. subtilis clock coordinates the spatiotemporal organisation of gene expression within expanding colonies by timing various processes to specific phases (times of day) within distinct colony regions. Our results support the idea that circadian clock-regulation over space, time and colony development in B. subtilis is analogous to circadian regulation of some processes in multicellular eukaryotes such as plants and mammals.

Indexed as

Bacillus subtilisCircadian ClocksBacterial ProteinsCircadian RhythmGene Expression Regulation, BacterialBacterial Proteins

Identifiers

PMID42315519
PMCPMC13434593

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.