Enantioselective construction of polychiral helical compounds via dynamic kinetic resolution.

Chengwen Li, Xiao-Qin Liu, Chen Yang, Ying-Bo Shao, Zhengxing Zhang, Xin Li

Abstract read

In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chengwen Li *State Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin, China.

Xiao-Qin Liu *State Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin, China.

Chen YangState Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin, China.ORCID http://orcid.org/0000-0002-2480-2855

Ying-Bo ShaoState Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin, China.

Zhengxing ZhangState Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin, China.

Xin LiState Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin, China. xin_li@nankai.edu.cn.ORCID http://orcid.org/0000-0001-6020-9170

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chiral helicenes and their derivatives are valuable across diverse research fields, yet the development of helical chirality has lagged far behind that of point and axial chirality. The synthesis of polychiral or heteroatom-containing helical systems remains especially challenging because of limited starting materials and difficulties in stereochemical control. Here we computationally design a flexible oxa[4]helicenoid-ol scaffold with an optimal rotational barrier (ΔG

Identifiers

PMID42315509

DOI10.1038/s41467-026-73870-y

PMCPMC13434152

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.