ArticleNature communications2026
Conformational landscape and ligand-dependent clustering of the human type 2 IP
Caifeng Liu, Yu-Jing Lan, Max G Kushner, Qingyu Tang, Erkan Karakas
Abstract read
In one paragraphArticle in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
5 authors.
Caifeng LiuDepartment of Molecular Physiology and Biophysics, Vanderbilt University, School of Medicine, Nashville, TN, USA.
Yu-Jing LanDepartment of Molecular Physiology and Biophysics, Vanderbilt University, School of Medicine, Nashville, TN, USA.ORCID 0000-0002-5971-5284 Max G KushnerDepartment of Cell and Developmental Biology, Vanderbilt University, School of Medicine, Nashville, TN, USA.
Qingyu TangDepartment of Molecular Physiology and Biophysics, Vanderbilt University, School of Medicine, Nashville, TN, USA.ORCID 0000-0002-5554-6540 Erkan KarakasDepartment of Molecular Physiology and Biophysics, Vanderbilt University, School of Medicine, Nashville, TN, USA. erkan.karakas@vanderbilt.edu.ORCID 0000-0001-6552-3185 Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ben Ho Park · 1995 to 2026
$172.8MTranslational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MARY Kay WASHINGTON · 2002 to 2026
$29.9MShop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6MThermo Scientific Glacios cryo-TEMS10OD030292 · OD · VANDERBILT UNIVERSITY · PI NAKAGAWA, TERUNAGA · 2021 to 2021
$2.0MStructure and function of inositol triphosphate receptorsR01GM141251 · NIGMS · VANDERBILT UNIVERSITY · PI KARAKAS, ERKAN · 2021 to 2024
$1.4MTFS Talos-L120C, a 120kV transmission electron microscope for structural studiesS10OD036307 · OD · VANDERBILT UNIVERSITY · PI NAKAGAWA, TERUNAGA · 2024 to 2024
$656kNetwork-Attached Biomedical Research Data Management SystemS10RR031634 · NCRR · VANDERBILT UNIVERSITY · PI SMITH, JARROD ANSON · 2011 to 2011
$600kSpinning Disk Super Resolution Confocal Microscope for the Vanderbilt Brain InstituteS10MH130456 · NIMH · VANDERBILT UNIVERSITY · PI SCHAFER, JENNY · 2023 to 2023
$598kNCI NIH HHS P30 CA068485NCRR NIH HHS S10 RR031634NEI NIH HHS P30 EY008126NIDDK NIH HHS P30 DK058404NIGMS NIH HHS R01 GM141251NIH HHS S10 OD030292NIH HHS S10 OD036307NIMH NIH HHS S10 MH130456U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) GM141251
6 · The paper itselfAbstract
Inositol 1,4,5-trisphosphate (IP
Indexed as
Inositol 1,4,5-Trisphosphate ReceptorsAdenosine TriphosphateCalciumCalcium SignalingCryoelectron MicroscopyHEK293 CellsHumansInositol 1,4,5-TrisphosphateLigandsModels, MolecularProtein BindingProtein ConformationAdenosine TriphosphateCalciumInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsLigands
Identifiers
PMID42315508
PMCPMC13433952
What OpenQuestion holds
Textmetadata
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