Evidence map›Paper›PMID 42315167›Full record

SynthesisAge and ageing2026

The impact of medication management interventions on healthcare utilisation in people with dementia: a systematic review with meta-analysis.

Jiefei Yu, Danijela Gnjidic, Xenia Nastatos, Mouna Sawan

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Age and ageing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiefei YuThe University of Sydney, School of Pharmacy, Faculty of Medicine and Health, Sydney, New South Wales, Australia.ORCID 0009-0004-2737-5694
Danijela GnjidicThe University of Sydney, School of Pharmacy, Faculty of Medicine and Health, Sydney, New South Wales, Australia.
Xenia NastatosThe University of Sydney, School of Pharmacy, Faculty of Medicine and Health, Sydney, New South Wales, Australia.
Mouna SawanThe University of Sydney, School of Pharmacy, Faculty of Medicine and Health, Sydney, New South Wales, Australia.ORCID 0000-0002-0565-3524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedication management interventions are designed to reduce medication-related harms in older people with dementia; however, their effect on healthcare utilisation remains unclear.

objectiveTo summarise the impact of medication management interventions on healthcare utilisation in people with dementia. DATA SOURCES: Embase, MEDLINE, Web of Science, Cochrane CENTRAL Register of Controlled Trials, CINAHL, PsycINFO. STUDY SELECTION: Interventional studies assessing the impact of medication management interventions on healthcare utilisation in people with dementia aged ≥65. DATA EXTRACTION AND SYNTHESIS: Eligible randomised controlled trials (RCTs) were meta-analysed with risk ratios (RR), 95% confidence intervals (CIs) using a fixed-effect model. Outcomes from non-randomised studies were summarised through narrative synthesis. MAIN OUTCOMES: Healthcare utilisation, including hospitalisation, emergency department visits, primary care and residential aged care home admissions.

resultsSeven RCTs and five non-randomised studies were eligible for inclusion. Common interventions were physician education (n = 5), physician and patient/carer education (n = 2), physician targeted prescribing reminders (n = 1) and multidisciplinary team-based interventions (n = 5). Among these, physician and patient/carer targeted education resulted in a reduction in all-cause hospitalisation (RR =0.92, 95% CI [0.84-0.99], P = .04) and emergency department visits (RR = 0.92, 95% CI [0.86-0.98], P = .007) while multidisciplinary team-based interventions were effective in reducing drug-related hospital readmission (Hazard Ratio = 0.49, 95% CI [0.27-0.90], P = .02).

conclusionThis review found that physician and patient/carer targeted education showed the most promising effect on all-cause hospitalisation and emergency department visits. Future research should develop tailored educational interventions that address key aspects of medication management to optimise healthcare utilisation in people with dementia.

Indexed as

DementiaMedication Therapy ManagementAdherence InterventionsAgedAged, 80 and overAge FactorsEmergency Room VisitsEmergency Service, HospitalHospitalizationHumansRandomized Controlled Trials as TopicRisk Factorsdementiahealthcare utilisationmedication managementolder peoplesystematic review

Identifiers

PMID42315167
PMCPMC13278762

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.