ArticleNMR in biomedicine2026
A System for Retrofitting Conventional MRI Systems for Simultaneous Multinuclear MRI/MRS.
Article in NMR in biomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Proton magnetic resonance imaging (MRI) and spectroscopy (MRS) are widely used in clinical and research applications. Recent interest in X-nuclei studies highlights their ability to provide additional biochemical information, but the intrinsically low X-nuclear signal-to-noise ratio (SNR) significantly increases scan time. Simultaneous (rather than serial) acquisition of multiple nuclei can significantly reduce experiment time, but most conventional MR systems lack this capability without modifications. We present a cost-effective system that enables simultaneous multinuclear imaging and spectroscopy on conventional MR spectrometers. Our approach offers enhanced flexibility for multinuclear experiments, supports multinuclear array receive capability, and maintains phase stability in the radio frequency (RF) chain. The proposed system comprised multiple transmit and receive mixing channels and a four-channel flexible local oscillator (LO) source. By interfacing with the spectrometer, simultaneous transmit and receive at different frequencies were achieved. The performance of the system was evaluated through bench measurement and phantom multinuclear MRI and MRS experiments. Transmit and receive channel isolation of better than 30 dB was measured on the bench. Simultaneous excitation and reception of
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