Evidence map›Paper›PMID 42314984›Full record

ArticleJournal of molecular biology2026

An Evolutionarily Conserved TUSC2-OSCP Interface Suggests a Mitochondrial Ca

Sergey V Ivanov, Roman V Uzhachenko, Sergei P Boudko, Anil Shanker, Sanika S Chirwa, Alla V Ivanova

Abstract read
In one paragraph

Article in Journal of molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sergey V IvanovDepartment of Biochemistry, Cancer Biology, Neuroscience, and Pharmacology, School of Medicine, Meharry Medical College, 1005 D.B. Todd Jr. Blvd, Nashville, TN 37208, USA. Electronic address: sergey.ivanov@mmc.edu.
Roman V UzhachenkoDepartment of Biochemistry, Cancer Biology, Neuroscience, and Pharmacology, School of Medicine, Meharry Medical College, 1005 D.B. Todd Jr. Blvd, Nashville, TN 37208, USA.
Sergei P BoudkoDepartment of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Biochemistry, Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA.
Anil ShankerDepartment of Biochemistry, Cancer Biology, Neuroscience, and Pharmacology, School of Medicine, Meharry Medical College, 1005 D.B. Todd Jr. Blvd, Nashville, TN 37208, USA; Department of Biomedical Sciences, School of Graduate Studies, Meharry Medical College, Nashville, TN 37208, USA; The Office for Research and Innovation, Meharry Medical College, Nashville, TN 37208, USA.
Sanika S ChirwaDepartment of Biochemistry, Cancer Biology, Neuroscience, and Pharmacology, School of Medicine, Meharry Medical College, 1005 D.B. Todd Jr. Blvd, Nashville, TN 37208, USA.
Alla V IvanovaDepartment of Biochemistry, Cancer Biology, Neuroscience, and Pharmacology, School of Medicine, Meharry Medical College, 1005 D.B. Todd Jr. Blvd, Nashville, TN 37208, USA.

Funding

AIM-AHEAD Coordinating Center - All Four CoresOT2OD032581 · OD · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI Paul Avillach, Bettina M. Beech · 2021 to 2026
$168.7M
Technologies and Resources CoreU54MD007593 · NIMHD · MEHARRY MEDICAL COLLEGE · PI ADUNYAH, SAMUEL EVANS · 2012 to 2018
$24.7M
Translational Pathology CoreU54CA163069 · NCI · MEHARRY MEDICAL COLLEGE · PI ADUNYAH, SAMUEL EVANS, STEWART, LAMONICA VANETTE · 2011 to 2025
$18.8M
Meharry RCMI Program in Women's Health ResearchG12MD007586 · NIMHD · MEHARRY MEDICAL COLLEGE · PI HILDRETH, JAMES E · 2012 to 2016
$7.8M
Meharry Center for Genome Research (MCGR)UH3HG013248 · NHGRI · MEHARRY MEDICAL COLLEGE · PI Anil Shanker · 2025 to 2026
$4.2M
Role of Fus1-mediated antitumor CD8T-NK crosstalk in Alzheimer's disease pathologySC1CA182843 · NCI · MEHARRY MEDICAL COLLEGE · PI SHANKER, ANIL · 2013 to 2020
$3.1M
Methamphetamine Research Program at Meharry Medical CollegeR24DA036420 · NIDA · MEHARRY MEDICAL COLLEGE · PI CHARLTON, CLIVEL G. · 2014 to 2018
$2.3M
Diversity Center for Genome Research at MeharryUG3HG013248 · NHGRI · MEHARRY MEDICAL COLLEGE · PI SHANKER, ANIL · 2023 to 2023
$866k
Live Cell Imaging Confocal Microscope SystemS10RR025497 · NCRR · MEHARRY MEDICAL COLLEGE · PI GOODWIN, JEFFREY SHAWN · 2010 to 2010
$419k
NCI NIH HHS SC1 CA182843NCI NIH HHS U54 CA163069NCRR NIH HHS S10 RR025497NHGRI NIH HHS UG3 HG013248NHGRI NIH HHS UH3 HG013248NIDA NIH HHS R24 DA036420NIH HHS OT2 OD032581NIMHD NIH HHS G12 MD007586NIMHD NIH HHS U54 MD007593
6 · The paper itself

Abstract

Mitochondrial ATP synthase (mATPS) has the capacity to regulate the permeability transition pore (mPTP) during Ca

Indexed as

CalciumMembrane ProteinsMitochondriaMitochondrial Membrane Transport ProteinsMitochondrial ProteinsMitochondrial Proton-Translocating ATPasesAmino Acid SequenceAnimalsEvolution, MolecularHumansMitochondrial Permeability Transition PoreModels, MolecularPhylogenyProtein BindingCalciumMembrane ProteinsMitochondrial Membrane Transport ProteinsMitochondrial Permeability Transition PoreMitochondrial ProteinsMitochondrial Proton-Translocating ATPasesoligomycin sensitivity-conferring proteincalcium-binding motifmetal ion coordinationmitochondrial ATP synthaseOSCP (ATP5PO)TUSC2 (FUS1)

Identifiers

PMID42314984
PMCPMC13334959

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.