Evidence map›Paper›PMID 42314669›Full record

ArticleStem cell reports2026

Cloud-connected pluripotent stem cell platform enhances scientific identity in underrepresented students.

Samira Vera-Choqqueccota, Drew Ehrlich, Vladimir Luna-Gomez, Sebastian Hernandez, Jesus Gonzalez-Ferrer, Hunter E Schweiger, Kateryna Voitiuk, Yohei Rosen, Kivilcim Doganyigit, Isabel Cline and 9 more

Abstract read
In one paragraph

Article in Stem cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Samira Vera-ChoqqueccotaGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Live Cell Biotechnology Discovery Lab, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Drew EhrlichGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Live Cell Biotechnology Discovery Lab, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Computational Media, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Vladimir Luna-GomezGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Live Cell Biotechnology Discovery Lab, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Molecular, Cellular and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Sebastian HernandezGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Live Cell Biotechnology Discovery Lab, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Electrical and Computer Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Jesus Gonzalez-FerrerGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Live Cell Biotechnology Discovery Lab, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Hunter E SchweigerGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Live Cell Biotechnology Discovery Lab, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Molecular, Cellular and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Kateryna VoitiukGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Live Cell Biotechnology Discovery Lab, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Electrical and Computer Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Yohei RosenGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Electrical and Computer Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Kivilcim DoganyigitGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Isabel ClineGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Live Cell Biotechnology Discovery Lab, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Molecular, Cellular and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Rebecca WardAlisal High School, Salinas, CA 93905, USA.
Erika YehBiotechnology Program, Berkeley City College, Berkeley, CA 94704, USA.
Karen H MigaGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Barbara Des RochersBiotechnology Program, Berkeley City College, Berkeley, CA 94704, USA.
Sri KurniawanGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Computational Media, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
David HausslerGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Live Cell Biotechnology Discovery Lab, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Kristian López VargasEconomics Department, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Mircea TeodorescuGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Live Cell Biotechnology Discovery Lab, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Department of Electrical and Computer Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Mohammed A Mostajo-RadjiGenomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; Live Cell Biotechnology Discovery Lab, University of California, Santa Cruz, Santa Cruz, CA 95064, USA. Electronic address: mmostajo@ucsc.edu.

Funding

Nanoparticle Tracking Analyzer (NTA) for the Center for Live Cell GenomicsRM1HG011543 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI HAUSSLER, DAVID H, SALAMA, SOFIE REDA · 2021 to 2025
$12.0M
Data Resource and Administrative Coordination Center for the Scalable and Systematic Neurobiology of Psychiatric and Neurodevelopmental Disorder Risk Genes ConsortiumU24MH132628 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI DAVID H HAUSSLER, Tomasz Nowakowski · 2023 to 2026
$7.9M
Human Brain Single-Cell Genomics ExplorerU24NS146314 · NINDS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI HAUSSLER, DAVID H, ZHU, JINGCHUN · 2025 to 2025
$3.7M
NHGRI NIH HHS RM1 HG011543NIMH NIH HHS U24 MH132628NINDS NIH HHS U24 NS146314
6 · The paper itself

Abstract

Stem cell research offers unique opportunities for authentic scientific engagement, yet infrastructure requirements have confined participation to elite institutions, perpetuating workforce disparities. We developed an integrated framework combining stem cell engineering, cloud-connected microscopy, and psychometric assessment. The framework integrates a doxycycline-inducible NGN2 mouse embryonic stem cell (mESC) system, low-cost cloud microscopy, and the Stem Cell Research Identity Scale (SCRIS). Implementation across a high school and a community college demonstrated significant increases in scientific identity. Students using differentiating PSCs showed broader science identity gains than those using neuroblastoma cells, particularly in competence, research readiness, and recognition. High school students showed enhanced research competence gains compared to community college students despite equivalent intervention duration. Demographic analyses revealed enhanced effectiveness for Hispanic and first-generation college students. This framework provides a scalable model for broadening participation in biomedical research.

Indexed as

Cloud ComputingPluripotent Stem CellsStudentsAnimalsCell DifferentiationFemaleHumansMicecloud microscopyneuronal differentiationremote experimentationscience identitySTEM education

Identifiers

PMID42314669
PMCPMC13385445

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.