Evidence map›Paper›PMID 42313704›Full record

ArticleGlia2026

Longitudinal Tracking of Astrocyte Reactivity During the Development of Chronic Orofacial Neuropathic Pain Using [

Lewis S Crawford, James W M Kang, OIivia I Davanzo, Hyunsol Lim, Sabrina Salberg, Marissa Srgo, Crystal Li, Gaelle M Emvalomenos, Bianca Jupp, Matthew Long and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Glia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lewis S CrawfordSchool of Medical Sciences [Neuroscience], The University of Sydney, Sydney, New South Wales, Australia.
James W M KangSchool of Medical Sciences [Neuroscience], The University of Sydney, Sydney, New South Wales, Australia.
OIivia I DavanzoSchool of Medical Sciences [Neuroscience], The University of Sydney, Sydney, New South Wales, Australia.
Hyunsol LimSchool of Medical Sciences [Neuroscience], The University of Sydney, Sydney, New South Wales, Australia.
Sabrina SalbergDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Marissa SrgoDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Crystal LiDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Gaelle M EmvalomenosSchool of Medical Sciences [Neuroscience], The University of Sydney, Sydney, New South Wales, Australia.
Bianca JuppDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Matthew LongThe Radiopharmaceutical Research Laboratory, The Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Wayne NoonanThe Radiopharmaceutical Research Laboratory, The Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Mohammad B HaskaliThe Radiopharmaceutical Research Laboratory, The Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Richelle MychasiukSchool of Medical Sciences [Neuroscience], The University of Sydney, Sydney, New South Wales, Australia.
Kevin A KeaySchool of Medical Sciences [Neuroscience], The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0003-3934-4380
Luke A HendersonSchool of Medical Sciences [Neuroscience], The University of Sydney, Sydney, New South Wales, Australia.

Funding

National Health and Medical Research Council 1130280
6 · The paper itself

Abstract

Chronic neuropathic pain represents a significant global health burden and is hypothesized to be maintained by an altered astrocyte-neuron interplay. Evidence of astrocyte contributions to neuropathic pain are derived from both post-mortem immunohistochemical analyses and in vivo pharmacological studies. These data cannot provide insights into dynamic changes in astrocytes within an individual as pain develops. Here, we present the first use of [

Indexed as

AstrocytesChronic PainFacial PainQuinolinesAnimalsDisease Models, AnimalFluorine RadioisotopesMaleMonoamine OxidasePositron-Emission TomographyRatsRats, Sprague-DawleyFluorine-18Fluorine RadioisotopesMonoamine OxidaseQuinolineschronic constriction injurychronic painGFAPgliaimmunohistochemistrymonoamine oxidase Bnucleus accumbensratspinal trigeminal nucleustrigeminal nerve

Identifiers

PMID42313704
PMCPMC13278361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.