ArticleMicrobiologyOpen2026
Antibiotic Resistance and Biofilm Gene Distribution in Colistin-Resistant Acinetobacter baumannii.
Article in MicrobiologyOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Acinetobacter baumannii, a multidrug-resistant opportunistic bacterium, poses a substantial hazard in hospital settings. The emergence of colistin- and tigecycline-resistant strains further limits treatment options and necessitates detailed investigation of resistance mechanisms. A total of 144 clinical A. baumannii isolates from multiple hospitals in Iran were identified using standard microbiological and molecular techniques. Antimicrobial susceptibility was assessed using both disk diffusion and broth microdilution techniques. Biofilm formation was quantified by crystal violet staining. Resistance and biofilm-related genes were detected by conventional polymerase chain reaction (PCR). The expression of key resistance genes (pmrA, pmrB, adeB, adeJ, and adeG) was evaluated by quantitative PCR (qPCR) in resistant isolates, and MLST was performed to determine the genetic relatedness among tigecycline- and colistin-resistant isolates. Resistance to colistin and tigecycline was observed in 3 (2.08%) and 2 (1.4%) isolates, respectively, and 90.9% of the isolates were biofilm producers, with higher odds of strong biofilm formation significantly correlating with the presence of bla
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