Mutating different α-tubulin acetylation sites has distinct effects on axon terminal morphogenesis in

Helen Than, Chloe J Welch, Ethan Schauer, Sophia P Trujillo, Jill Wildonger

Abstract read

In one paragraph

Article in Molecular biology of the cell, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

Update of
Mutating different α-tubulin acetylation sites has distinct effects on axon terminal morphogenesis in2025

5 · Who and what money

Authors and funding

5 authors.

Helen ThanPediatrics, University of California, San Diego, La Jolla, CA 92093.

Chloe J WelchBiological Sciences Graduate Program, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0002-8330-4901

Ethan SchauerPediatrics, University of California, San Diego, La Jolla, CA 92093.ORCID 0009-0009-2833-7119

Sophia P TrujilloSchool of Biological Sciences, Cell & Developmental Biology, University of California, San Diego, La Jolla, CA 92093.

Jill WildongerPediatrics, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0002-6462-5830

Funding

Mechanistic analysis of microtubule dynamics and stability in neuronsR01NS116373 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WILDONGER, JILL C · 2021 to 2025

$1.7M

NINDS NIH HHS R01 NS116373

6 · The paper itself

Abstract

Microtubules are created from uniform α- and β-tubulin building blocks but typically carry out a variety of specialized functions within a cell. The post-translational modification of tubulin is one means by which microtubule function can be tuned to match different cellular activities. While multiple sites of acetylation have been identified in tubulin, particularly α-tubulin, the effect(s) of acetylation at different sites on microtubule function remain poorly characterized. Here, we took a genetic approach in

Indexed as

AxonsDrosophila melanogasterTubulinAcetylationAnimalsDrosophila ProteinsMicrotubulesMorphogenesisMutationNeuronsProtein Processing, Post-TranslationalDrosophila ProteinsTubulin

Identifiers

PMID42313449

DOI10.1091/mbc.E25-10-0508

PMCPMC13428346

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.