Evidence map›Paper›PMID 42313228›Full record

Article3D printing in medicine2026

Development of a new operative 3D printed template-cranioplasty-concept for performing craniotomy in the posterior cranial fossa and validation of the system using a 3D printed simulation model: a preclinical feasibility study.

Svenja Jung, Maike Stummer, Christian König, Erdem Güresir, Dirk Winkler, Felix Arlt, Ronny Grunert

Abstract read
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Article in 3D printing in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Svenja JungDepartment of Neurosurgery, University of Leipzig, Leipzig, 04103, Germany. svenja.jung@medizin.uni-leipzig.de.
Maike StummerDepartment of Neurosurgery, University of Leipzig, Leipzig, 04103, Germany.
Christian KönigInstitute of Forensic Medicine, University of Leipzig, Leipzig, 04103, Germany.
Erdem GüresirDepartment of Neurosurgery, University of Leipzig, Leipzig, 04103, Germany.
Dirk WinklerDepartment of Neurosurgery, University of Leipzig, Leipzig, 04103, Germany.
Felix ArltDepartment of Neurosurgery, University of Leipzig, Leipzig, 04103, Germany.
Ronny GrunertDepartment of Neurosurgery, University of Leipzig, Leipzig, 04103, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe retrosigmoid approach is a standard surgical route used for the treatment of various tumors and vascular lesions in the cerebellopontine angle. However, postoperative reconstruction of the surgical defect could remain challenging, particularly in cases requiring intraoperative extension. For this reason, a novel concept was developed to define the surgical approach and enable precise defect coverage using a patient-specific implant. This concept was designed to be patient-specific and realized through 3D printing.

methodsThe developed 3D printed template-implant concept was designed to facilitate precise craniotomy. The template is used as a stencil and a surgical marker is applied to delineate the implant contours directly on the patient's skull. This outline subsequently serves as a guide for where to perform the craniotomy and defines its boundaries. The custom-fit implant replicates the template design and ensures complete coverage of the craniotomy defect, while allowing intraoperative adjustment if required. Preclinical testing was conducted on a 3D printed simulation model representing the posterior cranial fossa (surgical area). The novel concept was tested by nine senior and attending neurosurgeons from the University Hospital Leipzig. Bilateral craniotomies were performed using the template and subsequently closed with the implant. The fit of the implant was evaluated using CT scans. The time required for preparation, including craniotomy, as well as for post-procedure handling, including implant placement, was recorded.

resultsThe average gap of the new concept was 2.11 mm, which was significantly smaller than that of the current standard approach (5.52 mm) and showed lower variability. The entire procedure, including craniotomy and implant placement, took an average of 13 min and 20 s.

conclusionThe novel template-implant concept for retrosigmoid approaches improves defect coverage and reduces gap sizes. Furthermore, it demonstrates the potential of 3D printed patient-specific implants for more precise and predictable surgical procedures, although further studies are required to validate efficiency and clinical safety.

Indexed as

3D print3D printed templateAdditive manufacturingCranioplastyFossa cranii posteriorNeurosurgicalRetrosigmoid approach

Identifiers

PMID42313228
PMCPMC13285088

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