Evidence map›Paper›PMID 42313169›Full record

ArticleSurgery today2026

A soft tissue mass around the arteries after pancreatectomy: the association with local recurrence and the impact of neoadjuvant radiotherapy in pancreatic ductal adenocarcinoma.

Keisuke Toya, Yoshito Tomimaru, Hirofumi Akita, Yosuke Mukai, Kazuki Sasaki, Shinichiro Hasegawa, Daisaku Yamada, Takehiro Noda, Shogo Kobayashi, Atsushi Nakamoto and 2 more

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Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Keisuke ToyaDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2-E2, Yamadaoka, Suita, 565-0871, Osaka, Japan.
Yoshito TomimaruDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2-E2, Yamadaoka, Suita, 565-0871, Osaka, Japan.
Hirofumi AkitaDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2-E2, Yamadaoka, Suita, 565-0871, Osaka, Japan. hakita@gesurg.med.osaka-u.ac.jp.
Yosuke MukaiDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2-E2, Yamadaoka, Suita, 565-0871, Osaka, Japan.
Kazuki SasakiDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2-E2, Yamadaoka, Suita, 565-0871, Osaka, Japan.
Shinichiro HasegawaDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2-E2, Yamadaoka, Suita, 565-0871, Osaka, Japan.
Daisaku YamadaDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2-E2, Yamadaoka, Suita, 565-0871, Osaka, Japan.
Takehiro NodaDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2-E2, Yamadaoka, Suita, 565-0871, Osaka, Japan.
Shogo KobayashiDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2-E2, Yamadaoka, Suita, 565-0871, Osaka, Japan.
Atsushi NakamotoDepartment of Radiology, Graduate School of Medicine, The University of Osaka, Osaka, Japan.
Yuichiro DokiDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2-E2, Yamadaoka, Suita, 565-0871, Osaka, Japan.
Hidetoshi EguchiDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2-E2, Yamadaoka, Suita, 565-0871, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe presence of a soft tissue mass (STM) around the arteries is often observed after pancreatectomy. Although a STM frequently represents local recurrence, it can also reflect benign postoperative changes. However, the frequency of STMs and the factors determining whether its presence leads to local recurrence or remains benign have not been studied. This study aimed to determine the frequency of STM after pancreatectomy and to identify the clinical factors associated with the development of local recurrence.

methodsA total of 246 patients who underwent pancreatectomy at a single institution were analyzed retrospectively. The presence of a STM was assessed by follow-up computed tomography, and its association with local recurrence was evaluated.

resultsAmong the 246 patients, 33 (13.4%) developed STM after pancreatectomy, and all cases occurred in patients with pancreatic ductal adenocarcinoma (PDAC). Among the 133 patients who underwent pancreatectomy for PDAC, 33 (24.8%) developed STM, 23 (69.7%) of which progressed to local recurrence. No significant predictive factors for STM occurrence were identified in the PDAC patients. However, among the PDAC patients with STM, those who had received neoadjuvant radiotherapy were significantly less likely to develop local recurrence than those who had not (P = 0.0259).

conclusionSTMs occurred after pancreatectomy only in patients with PDAC, and neoadjuvant radiotherapy may influence whether the STM progresses to local recurrence, although the sample size was limited. No predictive factors associated with the development of STMs in patients with PDAC were identified.

Indexed as

ArteriesCarcinoma, Pancreatic DuctalNeoadjuvant TherapyNeoplasm Recurrence, LocalPancreatectomyPancreatic NeoplasmsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRadiotherapy, AdjuvantRetrospective StudiesTomography, X-Ray ComputedLocal recurrencePancreatectomyPancreatic cancerRadiotherapySoft tissue mass

Identifiers

PMID42313169

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.