Evidence map›Paper›PMID 42313113›Full record

ArticleAntimicrobial agents and chemotherapy2026

Acquired mutations in transcriptional regulator

Anna Schumann, Ian P O'Keefe, Robert K Ernst, Martin Wiedmann

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna SchumannDepartment of Food Science, Cornell University, Ithaca, New York, USA.ORCID 0000-0003-3627-9966
Ian P O'KeefeDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, Maryland, USA.ORCID 0000-0003-1151-3242
Robert K ErnstDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, Maryland, USA.ORCID 0000-0001-5016-8694
Martin WiedmannDepartment of Food Science, Cornell University, Ithaca, New York, USA.ORCID 0000-0002-4168-5662

Funding

Colistin-resistant Acinetobacter baumanniiR01AI104895 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DOI, YOHEI, ERNST, ROBERT K · 2014 to 2024
$4.2M
MS Diagnostic Bacterial Identification LibraryR01AI147314 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI ERNST, ROBERT K, GOODLETT, DAVID ROBINSON · 2020 to 2024
$2.3M
Systems-Level Research in Microbial PathogenesisT32AI162579 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI NICHOLAS H CARBONETTI, Julie Dunning Hotopp · 2022 to 2026
$1.7M
NIAID NIH HHS R01 AI104895NIAID NIH HHS R01 AI147314NIAID NIH HHS T32 AI162579NIH HHS 5T32AI162579-03NIH HHS AI104895NIH HHS AI147314
6 · The paper itself

Abstract

Gram-negative bacteria can develop resistance to the last-resort antimicrobial colistin through the acquisition of

Indexed as

Anti-Bacterial AgentsColistinDrug Resistance, BacterialEscherichia coliEscherichia coli ProteinsLipopolysaccharidesGene Expression Regulation, BacterialMicrobial Sensitivity TestsMutationTransferases (Other Substituted Phosphate Groups)Anti-Bacterial AgentsColistinEscherichia coli ProteinsLipopolysaccharidesMCR-3 protein, E coliTransferases (Other Substituted Phosphate Groups)colistinEscherichia colievolutionH-NSLpxCmcr

Identifiers

PMID42313113
PMCPMC13436332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.