Evidence map›Paper›PMID 42313059›Full record

ArticleMolecular pharmaceutics2026

Computational Identification of Active Drug Metabolites for Human Protein Targets.

Sofia Larsson, Rocío Mercado, Susanne Winiwarter, Filip Miljković

Abstract read
In one paragraph

Article in Molecular pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sofia LarssonDepartment of Computer Science and Engineering, Chalmers University of Technology and University of Gothenburg, Chalmersplatsen 1, 412 96 Gothenburg, Sweden.ORCID 0009-0007-2837-3617
Rocío MercadoDepartment of Computer Science and Engineering, Chalmers University of Technology and University of Gothenburg, Chalmersplatsen 1, 412 96 Gothenburg, Sweden.ORCID 0000-0002-6170-6088
Susanne WiniwarterDrug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Pepparedsleden 1, 431 83 Mölndal, Sweden.ORCID 0000-0002-9808-1683
Filip MiljkovićBiopharma Chemistry, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Pepparedsleden 1, 431 83 Mölndal, Sweden.ORCID 0000-0001-5365-505X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding drug metabolism helps mitigate toxicity risks and anticipate pharmacological effects beyond the parent compound. Here, we explore high-confidence

Indexed as

Computational BiologyDrug DiscoveryProteinsData MiningHumansPharmaceutical PreparationsPharmaceutical PreparationsProteinscompound bioactivitydata miningdrug discoverydrug metabolismpharmacokinetics

Identifiers

PMID42313059
PMCPMC13343518

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.