Evidence map›Paper›PMID 42313057›Full record

ArticleApplied and environmental microbiology2026

Positive epistasis among ribosomal mutations drives high-level streptomycin resistance in

Fengjun Xu, Yue Xing, Yujie Men

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fengjun XuDepartment of Chemical and Environmental Engineering, University of California, Riverside, Riverside, California, USA.ORCID 0000-0002-6627-2610
Yue XingDepartment of Chemical and Environmental Engineering, University of California, Riverside, Riverside, California, USA.
Yujie MenDepartment of Chemical and Environmental Engineering, University of California, Riverside, Riverside, California, USA.ORCID 0000-0001-9811-3828

Funding

National Science Foundation 2045658
6 · The paper itself

Abstract

The widespread use of antibiotics has raised serious concerns about the emergence and dissemination of antibiotic resistance in the environment. Studies reveal that environmental exposures to sub-inhibitory level antibiotics and other low-level non-antibiotic pollutants can promote the development of high-level antibiotic resistance via

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialEpistasis, GeneticEscherichia coliRibosomal ProteinsRibosomesStreptomycinEscherichia coli ProteinsMutationAnti-Bacterial AgentsEscherichia coli ProteinsRibosomal ProteinsRpsL protein, E coliStreptomycinantibiotic resistancepositive epistasisrpsErpsLrsmGstreptomycin

Identifiers

PMID42313057
PMCPMC13390409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.