Evidence map›Paper›PMID 42313036›Full record

ArticleJACC. Case reports2026

Combined Heart-Lung Transplant for Pulmonary Artery Aneurysm Secondary to Pulmonary Arterial Hypertension.

Ajay P Kerai, A Cozette Killian, Charles W Hoopes, Eric Orozco-Hernandez

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ajay P KeraiDepartment of Advanced Heart Failure and Transplantation Cardiology, University of Alabama at Birmingham, Birmingham, Alabama, USA. Electronic address: aju.kerai89@gmail.com.
A Cozette KillianDivision of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Charles W HoopesDivision of Cardiothoracic Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Eric Orozco-HernandezDivision of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary artery aneurysms (PAAs) are rare occurring in approximately 1 in 14,000 cases. While PAA is frequently associated with pulmonary arterial hypertension (PAH), the optimal management strategy remains undefined due to the rarity of the disease. CASE SUMMARY: We report a case of a 58-year-old female with longstanding idiopathic PAH who underwent combined heart-lung transplantation to treat a rapidly expanding 8.95-cm PAA with associated cor pulmonale and severe pulmonic valve regurgitation. Graft function remained excellent; however, an ischemic stroke in the postoperative period led to significant morbidity. DISCUSSION: Despite the known association of PAA with PAH, specific treatment guidelines are lacking. Delay in intervention can lead to poor surgical candidacy and adverse outcomes. TAKE-HOME MESSAGES: PAA may progress despite stable PAH hemodynamics. Combined heart-lung transplantation can be a viable option for select patients with severe PAH, giant PAA, cor pulmonale, and severe pulmonic valve regurgitation.

Indexed as

combined heart-lung transplantpulmonary artery aneurysmpulmonary hypertension

Identifiers

PMID42313036
PMCPMC13531060

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.