Percutaneous Closure of Left Ventricular Apex Perforation After Transcatheter Aortic Valve Replacement Valve-in-Valve.

Andrew Moussad, Kaleab Asrress, Ata Doost

Abstract readCase Reports

In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Andrew MoussadDepartment of Cardiology, Nepean Hospital, Kingswood, New South Wales, Australia; Nepean Clinical School, Faculty of Medicine and Health, Charles Perkins Centre Nepean, The University of Sydney, Camperdown, New South Wales, Australia; Department of Cardiology, Macquarie University Hospital, Macquarie Park, New South Wales, Australia. Electronic address: andrew_moussad@hotmail.com.

Kaleab AsrressDepartment of Cardiology, Macquarie University Hospital, Macquarie Park, New South Wales, Australia; Department of Cardiology, Bankstown Hospital, Bankstown, New South Wales, Australia.

Ata DoostDepartment of Cardiology, Macquarie University Hospital, Macquarie Park, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscatheter aortic valve replacement (TAVR) valve-in-valve (ViV) is a less invasive alternative to redo surgery for high-risk patients with failed bioprosthetic aortic valves. Left ventricular (LV) perforation is a rare but potentially life-threatening complication, typically requiring surgical repair. Percutaneous closure is seldom reported. CASE SUMMARY: An 80-year-old man with NYHA functional class III symptoms from severe degenerative transvalvular bioprosthetic aortic regurgitation underwent TAVR ViV. Postprocedure transthoracic echocardiogram and computed tomography scan revealed a small, contained LV apex perforation, likely iatrogenic from guidewire manipulation. This was successfully closed percutaneously using an Amplatzer Vascular Plug II. DISCUSSION: This case highlights importance of high-quality post-TAVR ViV transthoracic echocardiography and safety of percutaneous closure of LV apex perforation compared with surgical repair. TAKE-HOME MESSAGES: LV apex perforation is a rare but serious complication of TAVR. Percutaneous closure may avoid high-risk surgery in suitable cases.

Indexed as

Amplatzer Vascular Plugaortic regurgitationbioprosthetic valve failurecardiac imagingiatrogenic complicationtranscatheter intervention

Identifiers

PMID42313034

DOI10.1016/j.jaccas.2026.108893

PMCPMC13480131

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.