SynthesisBipolar disorders2026
Effectiveness of Family Interventions in Bipolar Disorder: A Systematic Review.
Synthesis in Bipolar disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionBipolar disorder (BD) is a chronic mental health condition characterized by extreme mood swings, which significantly affects both the individual and their family system. Given the psychosocial impact of BD on families, family interventions (FI) have emerged as a promising approach to improve treatment outcomes. This review explores the effectiveness of FI in managing BD, focusing on various intervention types, their outcomes, and clinical implications.
methodsThis review followed PRISMA guidelines and registered with PROSPERO (registration number: CRD42023410879). We included studies involving adults diagnosed with BD and their family members, focusing on family-based interventions. Studies were identified through systematic searches in five bibliographic databases and managed using Covidence 2.0. Data extraction and synthesis included primary and secondary outcomes related to clinical, behavioral, and lifestyle measures. Risk of bias was assessed using the Joanna Briggs Institute (JBI) critical appraisal tool for quasi-experimental studies.
resultsFamily-focused interventions were found to reduce relapse rates, enhance medication adherence, and improve family communication. Psychoeducational interventions also demonstrated a significant reduction in symptom severity and hospitalization rates. However, findings regarding the long-term sustainability of these outcomes were mixed, and some interventions showed limited generalizability across diverse family structures and cultural contexts.
conclusionFIs are critical in treating BD by improving both clinical and relational outcomes. However, the heterogeneity of family structures and cultural factors calls for more tailored approaches to ensure long-term efficacy. Future research should focus on developing culturally sensitive interventions and exploring the mechanisms by which family dynamics influence treatment adherence and recovery in BD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.