Evidence map›Paper›PMID 42312806›Full record

ArticleDrug testing and analysis2026

Chemical Characterization of an Emerging Designer Steroid, 6-Bromo-androst-4-en-3,17-dione, via NMR and LC-HRMS and GC-HRMS.

Genye He, Sisi Zhu, Xin Liu, Zhanliang Wang, Lisi Zhang, Jianghai Lu, Jing Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug testing and analysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Genye HeDepartment of Chemistry, China Agricultural University, Beijing, China.ORCID https://orcid.org/0000-0002-2786-6600
Sisi ZhuBeijing Anti-Doping Laboratory, Beijing Sport University, Beijing, China.ORCID https://orcid.org/0000-0001-8631-1069
Xin LiuBeijing Anti-Doping Laboratory, Beijing Sport University, Beijing, China.
Zhanliang WangBeijing Anti-Doping Laboratory, Beijing Sport University, Beijing, China.
Lisi ZhangBeijing Anti-Doping Laboratory, Beijing Sport University, Beijing, China.ORCID https://orcid.org/0009-0006-0164-8230
Jianghai LuDoping Prevention Scientific Research Laboratory, China Anti-Doping Agency, Beijing, China.
Jing LiDepartment of Chemistry, China Agricultural University, Beijing, China.

Funding

World Anti-Doping Agency 253A01JL
6 · The paper itself

Abstract

A package of raw material, deliberately mislabelled as a muscle-building supplement, was obtained online to contain an unknown steroid. In order to accurately identify the composition of the substance, we used a combination of advanced techniques: liquid and gas chromatography coupled with high-resolution mass spectrometry (GC-HRMS and LC-HRMS), alongside nuclear magnetic resonance (NMR) spectroscopy. By combining the strengths of these methods, we successfully identified the compound as 6-Bromo-androst-4-en-3,17-dione (6-BrAED). This substance is a designer steroid of testosterone that is not currently on the World Anti-Doping Agency (WADA) prohibited list. As it is unlisted, there is a serious hidden risk that athletes could take it by accident through contaminated supplements.

Indexed as

Designer DrugsAnabolic Androgenic SteroidsChromatography, LiquidDoping in SportsGas Chromatography-Mass SpectrometryHumansLiquid Chromatography-Mass SpectrometryMagnetic Resonance SpectroscopySteroidsAnabolic Androgenic SteroidsDesigner DrugsSteroids6‐bromo‐androst‐4‐en‐3,17‐dionedegradationdopingsteroids

Identifiers

PMID42312806
PMCPMC13432699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.