Evidence map›Paper›PMID 42312786›Full record

ArticleJACC. Advances2026

Clinical Characteristics and Outcomes of Older Patients Admitted to the Cardiac Intensive Care Unit.

Constantine Tarabanis, Jianping Guo, Gregory W Barsness, Maryam Farahmandsadr, Christopher B Fordyce, Michael Goldfarb, Jason N Katz, Michael C Kontos, P Elliott Miller, L Kristin Newby and 3 more

Abstract read
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Article in JACC. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Constantine TarabanisCardiology Division, Heart and Vascular Institute, Mass General Brigham, Boston, Massachusetts, USA. Electronic address: ctarabanis@mgh.harvard.edu.
Jianping GuoLevine Cardiac Intensive Care Unit, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Gregory W BarsnessDivision of Critical Care Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Maryam FarahmandsadrDivision of Cardiology, University of Florida College of Medicine, Jacksonville, Florida, USA.
Christopher B FordyceDivision of Cardiology, Vancouver General Hospital, and the Center for Cardiovascular Innovation, University of British Columbia, Vancouver, British Columbia, Canada.
Michael GoldfarbDivision of Cardiology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.
Jason N KatzDivision of Cardiology, New York University Grossman School of Medicine & Bellevue Hospital, New York, New York, USA.
Michael C KontosDivision of Cardiology, Virginia Commonwealth University, Richmond, Virginia, USA.
P Elliott MillerSection of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
L Kristin NewbyDivision of Cardiology, Department of Medicine, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA.
Sean van DiepenDepartment of Critical Care Medicine and Division of Cardiology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
David A MorrowLevine Cardiac Intensive Care Unit, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Carlos L AlviarDivision of Cardiology, New York University Grossman School of Medicine & Bellevue Hospital, New York, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundContemporary data characterizing older adults admitted to cardiac intensive care units (CICUs) across diverse indications are limited.

objectivesThe objective of the study was to describe the clinical characteristics, critical care therapies, and in-hospital outcomes of older patients admitted to the CICU compared with younger adults.

methodsThe Critical Care Cardiology Trials Network is a multicenter, international registry of CICUs. Between 2017 and 2024, participating centers contributed annual ≥2-month snapshots of consecutive medical CICU admissions. Admissions were categorized into 4 age groups: <65, 65-<75, 75-<85, and ≥85 years. Outcomes included CICU and in-hospital mortality and length of stay. Multivariable models adjusted for sex, illness severity (SOFA score), lactate, and kidney function.

resultsAmong 35,265 admissions from 50 sites, 44%, 27%, 21%, and 9% were aged <65, 65-<75, 75-<85, and ≥85 years, respectively. Acute coronary syndrome was the most common admission diagnosis among all age groups. Patients aged ≥85 years had the lowest use of mechanical circulatory support (5.5%), which consisted exclusively of intra-aortic balloon pumps. Relative to patients <65 years, adjusted ORs of in-hospital mortality were 1.53 (1.40-1.67) for 65-<75 years, 1.83 (1.67-2.01) for 75-<85 years, and 1.95 (1.72-2.22) for ≥85 years. Among cardiac arrest patients the increase in mortality with age was steeper, reaching 3.09 (2.24-4.26) for patients ≥85 years.

conclusionsPatients ≥85 years in contemporary CICUs experience survival comparable to those aged 75-<85 years, except in the setting of cardiac arrest. These findings support consideration of factors beyond chronological age in CICU triage and treatment decisions.

Indexed as

cardiac arrestcardiac intensive care unitcardiogenic shockcritical care cardiologygeriatricsin-hospital mortality

Identifiers

PMID42312786
PMCPMC13308241

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.