Evidence map›Paper›PMID 42312749›Full record

ArticleJACC. Case reports2026

Lyme Carditis in a Transplanted Heart: A Rare Cause of Early Conduction Abnormalities.

Brian Del Pino, Merna Hussien, Sachin Mehta, Aferdita Spahillari, Jacob Schroder, Elizabeth N Pavlisko, Huihua Li, Cameron Wolfe, Michael Cutrone

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Brian Del PinoDivision of Cardiothoracic Anesthesiology, Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA. Electronic address: brian.delpino@duke.edu.
Merna HussienDivision of Cardiology, Duke University Medical Center, Durham, North Carolina, USA.
Sachin MehtaDivision of Cardiothoracic Anesthesiology, Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA.
Aferdita SpahillariDivision of Cardiology, Duke University Medical Center, Durham, North Carolina, USA.
Jacob SchroderDivision of Cardiovascular and Thoracic Surgery, Duke University Medical Center, Durham, North Carolina, USA.
Elizabeth N PavliskoDepartment of Pathology, Duke University Medical Center, Durham, North Carolina, USA.
Huihua LiDepartment of Pathology, Duke University Medical Center, Durham, North Carolina, USA.
Cameron WolfeDivision of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, USA.
Michael CutroneDivision of Cardiothoracic Anesthesiology, Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLyme disease, caused by Borrelia burgdorferi, is the most common vector-borne infection in North America. Cardiac involvement occurs in approximately 1% to 10% of untreated infections and most commonly manifests as atrioventricular conduction abnormalities. CASE SUMMARY: A 29-year-old man with arrhythmogenic right ventricular cardiomyopathy underwent orthotopic heart transplantation. Early postoperatively he developed atrial flutter progressing to complete heart block despite preserved graft function and absence of rejection. Donor history revealed recent tick exposure. Warthin-Starry staining of surveillance endomyocardial biopsy demonstrated rare spirochetes consistent with Borrelia species. The patient received intravenous ceftriaxone for presumed donor-derived Lyme carditis but ultimately required permanent pacemaker implantation. DISCUSSION: This case highlights Lyme carditis as a rare potential cause of early conduction abnormalities after heart transplantation.

Indexed as

atrioventricular blockBorrelia burgdorferidonor-derived infectionheart transplantationLyme carditis

Identifiers

PMID42312749
PMCPMC13309727

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