Evidence map›Paper›PMID 42312457›Full record

ArticleImmunotherapy2026

Exploring global research trends in sublingual immunotherapy of allergic rhinitis: a comprehensive bibliometric analysis.

Wenzhe Gu, Zhengjie Shen, Jun Shi, Hao Xu, Hongjun Dong, Daonan Yan, Yunfeng Chu

Abstract read
In one paragraph

Article in Immunotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenzhe GuDepartment of Otolaryngology, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, China.
Zhengjie ShenDepartment of Oncology Department, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, China.
Jun ShiDepartment of Otolaryngology, Jiangsu Provincial Hospital of Traditional Chinese, Nanjing, China.
Hao XuDepartment of Otolaryngology, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, China.
Hongjun DongDepartment of Otolaryngology, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, China.
Daonan YanDepartment of Otolaryngology, Jiangsu Provincial Hospital of Traditional Chinese, Nanjing, China.
Yunfeng ChuDepartment of Otolaryngology, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsSublingual immunotherapy (SLIT) is a well-established, safe, and patient-friendly treatment for allergic rhinitis. This study aims to provide a comprehensive bibliometric analysis of global research trends and emerging hotspots in SLIT for allergic rhinitis.

methodsRelevant publications were sourced from the Web of Science Core Collection (1993-2024). VOSviewer, CiteSpace, and the R "bibliometrix" package were used to visualize research collaborations, leading contributors, and thematic developments.

resultsThis analysis of 696 publications on SLIT for allergic rhinitis reveals a dynamic, collaborative field. The USA, China, and Italy led production, with the University of Genoa as the top institution. Research is organized into six clusters: immunological mechanisms, clinical efficacy, epidemiology/guidelines, pediatric research, disease classification, and real-world evidence.The focus has evolved over two decades from initial clinical efficacy studies toward understanding underlying immune mechanisms (highlighted by recent keyword bursts like "dendritic cells"), biomarker discovery, and specialized pediatric applications. There is also a strengthened emphasis on long-term management and real-world effectiveness.

conclusionSLIT research is diversifying, marked by a growing emphasis on immunology, personalized and pediatric approaches, and practical outcomes, providing a robust foundation for optimizing future therapy.

Indexed as

Rhinitis, AllergicSublingual ImmunotherapyBibliometricsBiomedical ResearchHumansallergic rhinitisBibliometric analysisexploring global research trendssublingual immunotherapyvisual analysis

Identifiers

PMID42312457
PMCPMC13348961

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.