Evidence map›Paper›PMID 42312381›Full record

Observational studyCirculation2026

Mechanical CPR Device Use and Cardiac Arrest Survival in EMS Agencies.

Paul S Chan, Bryan F McNally, Zhuxuan Fu, Rabab Al-Araji, Saket Girotra

Abstract readObservational Study
In one paragraph

Observational study in Circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paul S ChanDepartment of Internal Medicine, Saint Luke's Mid America Heart Institute, Kansas City, MO (P.S.C., Z.F.).ORCID 0000-0002-5185-3367
Bryan F McNallyDepartment of Internal Medicine, Rollins School of Public Health and Emory University School of Medicine, Atlanta, GA (B.F.M.).ORCID 0000-0003-3532-1931
Zhuxuan FuDepartment of Internal Medicine, Saint Luke's Mid America Heart Institute, Kansas City, MO (P.S.C., Z.F.).ORCID 0000-0002-9190-195X
Rabab Al-ArajiDepartment of Internal Medicine, Emory University, Atlanta, GA (R.A.A).
Saket GirotraDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas (S.G.).ORCID 0000-0002-4784-4513

Funding

Reducing Ethnic-racial Disparities in Cardiac Arrest Survival Outcomes (RED-CASO)R01HL160734 · NHLBI · SAINT LUKE'S HOSPITAL · PI CHAN, PAUL SHEUNG-YAN, GIROTRA, SAKET · 2022 to 2025
$2.6M
Peripheral Artery Disease: Long-term Survival & Outcomes Study (PEARLS)R01HL166305 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI Saket Girotra · 2023 to 2026
$2.5M
Improving Quality in Cardiac Arrest via Resuscitation academy Training: The IQ-CART studyR01HL178638 · NHLBI · SAINT LUKE'S HOSPITAL · PI Paul Sheung-Yan Chan · 2025 to 2026
$1.1M
NHLBI NIH HHS R01 HL160734NHLBI NIH HHS R01 HL166305NHLBI NIH HHS R01 HL178638
6 · The paper itself

Abstract

backgroundCardiopulmonary resuscitation (CPR) by health care responders is often suboptimal during out-of-hospital cardiac arrest (OHCA). Mechanical CPR devices have been promoted as a strategy to improve CPR quality. Whether their use in routine care is associated with improved OHCA survival at emergency medical service (EMS) agencies is unclear.

methodsWithin the Cardiac Arrest Registry to Enhance Survival, we assessed agency-level rates of OHCA survival at EMS agencies with ≥2 years of OHCA data before and after their first documented use of a mechanical CPR device from 2013 to 2019 using an observational cohort study design. Temporal trends in favorable neurological survival (without severe neurological disability) and survival to discharge were first assessed in EMS agencies that did not initiate mechanical CPR device use (control agencies) using multivariable hierarchical logistic regression. Then an interrupted time series analysis evaluated whether introduction of mechanical CPR devices at EMS agencies was associated with higher OHCA survival.

resultsAmong 51 994 patients with OHCA at 73 control agencies, there were no temporal trends in risk-adjusted rates of favorable neurological survival (annual rates ranged between 9.6% and 10.6%;

conclusionsIn a large US registry of OHCA, EMS agency rates of favorable neurological survival and survival to discharge were not higher after the initiation of mechanical CPR device use.

Indexed as

Cardiopulmonary ResuscitationEmergency Medical ServicesOut-of-Hospital Cardiac ArrestAgedFemaleHumansMaleMiddle AgedRegistriescardiac arrestCPRsurvival

Identifiers

PMID42312381
PMCPMC13286238

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.