ArticleFrontiers in global women's health2026
Partnership as a modulator of the effects of hormone replacement therapy in menopause.
Article in Frontiers in global women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To evaluate the influence of partnership status on the perception of menopausal symptoms and quality of life in women undergoing hormone replacement therapy (HRT). Methods: The study included 60 menopausal women aged 40-85 years with significant climacteric symptoms. Participants were divided into two groups according to relationship status: women living in a stable partnership ( Results: HRT was associated with improvement in menopausal symptoms and quality of life in both groups. However, women living in a partnership showed a greater reduction in MRS scores and a greater increase in MANSA scores compared to women without a partner. After three months of HRT, statistically significant correlations ( Conclusion: HRT improves menopausal symptoms and quality of life; however, partnership status appears to play a moderating role. A stable partnership may facilitate the integration of psychobiological processes of hormonal changes and contribute to improved subjective adaptation to menopause.
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