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Head and Neck Manifestations in Sarcoidosis: An All of Us Research Program Matched Case-Control Study.
Article in OTO open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aims to assess the prevalence of head and neck (ENT) symptoms in patients with sarcoidosis. Study Design: 1:4 matched-case control study. Setting: Patients with and without sarcoidosis who enrolled in the All of Us Research Program and consented to electronic medical record use. Methods: Multivariate logistic regression examined the association between ENT symptoms and sarcoidosis, adjusting for autoimmune status, the Charlson Comorbidity Index score, and smoking status. Results: A total of 2446 patients with sarcoidosis were matched to 9783 controls. Compared to age-, sex-, race-, and ethnicity-matched controls and after adjustment, patients with sarcoidosis are more likely to have a recorded diagnosis of sinonasal symptoms, including chronic rhinitis (adjusted OR: 2.061 (95% CI: 1.779-2.387), Conclusion: Patients with sarcoidosis are significantly more likely to be diagnosed with sinonasal symptoms, airway and swallowing symptoms, and cranial nerve pathologies with prevalence rates higher than previously reported. Sarcoidosis of the upper airway is likely underdiagnosed and consequently undertreated, necessitating greater awareness and further exploration of the etiology of upper airway symptoms in patients with sarcoidosis.
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