ArticleACS pharmacology & translational science2026
Efficient Elimination of Microbial Infections in Wounds Using Plasma-Activated Water Hydrogel.
Article in ACS pharmacology & translational science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Surgical site infections are among the most prevalent postoperative complications and remain a pressing global health challenge, exacerbated by the rise of antimicrobial resistance. Plasma-activated water (PAW) has recently gained attention as an innovative antimicrobial approach. However, earlier research indicated that its effectiveness relies on maintaining an acidic pH. To address this, we previously created a high-strength, neutral pH-buffered version (hs-PAbW) that is better suited for clinical use in humans. This neutral plasma activated water retained the potent antimicrobial activity. In this study, we engineered a hydrogel containing hs-PAbW at a bactericidal yet noncytotoxic dose (hs-PAbW-20) and assessed its efficacy in murine wound models. In BALB/c mice, hs-PAbW-20 gel significantly reduced
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