ArticleFrontiers in health services2026
Ten-year trends and influencing factors of hospitalization costs in chronic obstructive pulmonary disease: a quantile regression analysis (2016-2025).
Article in Frontiers in health services, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: To investigate the composition, temporal trends, and factors associated with per-admission hospitalization costs for chronic obstructive pulmonary disease (COPD)-related admissions from 2016 to 2025, adjusted for inflation and temporal effects, and to inform clinical cost control and optimized management strategies. Methods: We analyzed 4,766 COPD admissions events to a tertiary hospital in Guangxi, China. Descriptive analysis characterized cost trends and composition, followed by nonparametric tests, multiple linear regression, and quantile regression to identify cost-influencing factors. Results: Among the 4,766 eligible admissions, 75.9% ( Conclusion: Inflation-adjusted per-admission COPD hospitalization costs were stable over the decade, driven by drugs, medical services and diagnostics. Admission year, age, comorbidity count, LOS, invasive procedures and acute critical admission correlated with higher costs, with stronger associations in high-cost admissions. These findings support the development of targeted interventions for cost containment and standardized clinical management of COPD.
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