Evidence map›Paper›PMID 42312111›Full record

ArticleInternational journal of reproductive biomedicine2026

Effects of chrysin on Kisspeptin, neurokinin B, and dynorphin neurons and

Khadijeh Haghighat, Fariba Mahmoudi, Homayoun Khazali

Abstract read
In one paragraph

Article in International journal of reproductive biomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Khadijeh HaghighatDepartment of Biology, Faculty of Sciences, University of Mohaghegh Ardabili, Ardabil, Iran.
Fariba MahmoudiDepartment of Biology, Faculty of Sciences, University of Mohaghegh Ardabili, Ardabil, Iran.
Homayoun KhazaliDepartment of Animal Sciences and Marine Biology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A subpopulation of neurons known as Kisspeptin, neurokinin B, and dynorphin (KNDy) are located in the hypothalamus. These neurons co-express and release the corresponding neuropeptides. KNDy neurons are important in the reproductive process and can be affected by a number of factors, such as stress. Objective: To investigate the effect of chrysin as an anti-stress agent on the gene expression of hypothalamic Kisspeptin( Materials and Methods: In this experimental study, 30 male Wistar rats (200 Results: Expression of Conclusion: Chrysin may regulate the reproductive axis via modulation of hypothalamic

Indexed as

ChrysinDynorphinGonadotropin-releasing hormoneKisspeptinNeurokinin BRat.

Identifiers

PMID42312111
PMCPMC13270201

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.